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Editorial
September 2, 2025
- From data to policy: addressing the economic burden of biopsy-proven kidney diseases
- Hyung Woo Kim
- Kidney Res Clin Pract. 2026;45(2):143-145.
- Editorials
- From data to policy: addressing the economic burden of biopsy-proven kidney diseases
- Hyung Woo Kim
- Kidney Res Clin Pract. 2026;45(2):143-145. Published online September 2, 2025
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- Promising roles and current limitations of bortezomib-based desensitization for kidney transplantation
- Hee Byung Koh, Jaeseok Yang
- Kidney Res Clin Pract. 2026;45(2):146-149. Published online September 30, 2025
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- Special Article
- Are your kidneys okay? Detect early to protect kidney health
- Joseph A. Vassalotti, Anna Francis, Augusto Cesar Soares Dos Santos Jr, Ricardo Correa-Rotter, Dina Abdellatif, Li-Li Hsiao, Stefanos Roumeliotis, Agnes Haris, Latha A. Kumaraswami, Siu-Fai Lui, Alessandro Balducci, Vassilios Liakopoulos
- Kidney Res Clin Pract. 2026;45(2):150-159. Published online June 30, 2025
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Early identification of kidney disease can protect kidney health, prevent kidney disease progression and related complications, reduce cardiovascular disease risk, and decrease mortality. We must ask “Are your kidneys ok?” using serum creatinine to estimate kidney function and urine albumin to assess for kidney and endothelial damage. Evaluation for causes and risk factors for chronic kidney disease (CKD) includes testing...
- Review Articles
- Pathophysiology and potential treatment of uremic sarcopenia
- Shao-Yu Yang, Jia-Huang Chen, Chih-Kang Chiang, Kuan-Yu Hung
- Kidney Res Clin Pract. 2026;45(2):160-173. Published online February 21, 2025
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Sarcopenia, commonly found in the elderly and characterized by the loss of skeletal muscle mass, decreased muscle strength, and reduced physical performance, draws attention because it often leads to frailty, an increased risk of falls and fractures, and higher morbidity and mortality. Patients with chronic kidney disease (CKD) usually suffer from malnutrition, physical inactivity, inflammation, metabolic acidosis, insulin resistance, and...
- Sarcopenia, sarcopenic obesity, and frailty in individuals with chronic kidney disease: a comprehensive review
- Chia-Ter Chao, Csaba P. Kovesdy, Reshma Aziz Merchant
- Kidney Res Clin Pract. 2026;45(2):174-188. Published online January 21, 2025
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Population aging is a global challenge that increases the burden of chronic kidney disease (CKD) and geriatric syndromes such as sarcopenia, sarcopenic obesity, and frailty. These conditions affect almost half of older CKD individuals and are associated with poor outcomes, including CKD progression, cardiometabolic complications, increased health and social care costs, and mortality. They can be both the cause and...
- Novel insights and practical strategies for health professionals to improve the uptake of plant-based diets in people with chronic kidney disease
- Kelly Lambert, Vanessa Cullen, Brian Jones, Amy McAlpine, Brad Rossiter
- Kidney Res Clin Pract. 2026;45(2):189-197. Published online February 18, 2025
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There has been a significant shift in dietary guidance in the past 5 years for people with chronic kidney disease. Multiple best practice guidelines in nephrology now include nutritional guidance that recommends the adoption of healthy dietary patterns with an emphasis on whole foods and diets with adequate fruit, vegetables, legumes, nuts, wholegrain bread and cereals, with minimal amounts of...
- Original Articles
- Predicting long-term mortality of patients with postoperative acute kidney injury following noncardiac general anesthesia surgery using machine learning
- Bo Yeon Choi, Wona Choi, Jiwon Min, Byung Ha Chung, Eun Sil Koh, Su Yeon Hong, Tae Hyun Ban, Yong Kyun Kim, Hye Eun Yoon, In Young Choi
- Kidney Res Clin Pract. 2026;45(2):198-209. Published online September 26, 2024
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Background: This study addresses the gap in knowledge regarding the long-term mortality implications of postoperative acute kidney injury (PO-AKI) utilizing advanced machine learning techniques to predict outcomes more accurately than traditional statistical models. Methods: A retrospective cohort study was conducted using data from seven institutions between March 2009 and December 2019. Machine learning models were developed to predict all-cause mortality of...
- Medical costs in the peridiagnosis period of various biopsy-confirmed kidney diseases in South Korea
- Young Sun Shin, Kyungdo Han, Sehoon Park, Kwon Wook Joo, Jeong Min Cho, Yeojin Yu, Soojin Lee, Yaerim Kim, Semin Cho, Hyuk Huh, Seong Geun Kim, Eun Jeong Kang, Dong Ki Kim
- Kidney Res Clin Pract. 2026;45(2):210-219. Published online September 11, 2024
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Background: In-depth investigation is imperative to scrutinize medical costs associated with the periods before and after biopsies for diverse kidney diseases in South Korea. Long-term epidemiological data, including follow-up information, is essential for comparing risks linked to various kidney diseases and their adverse outcomes. Methods: Patients diagnosed with glomerulonephritis (GN), tubulointerstitial nephritis (TIN), and acute tubular necrosis (ATN) at Seoul...
- Evaluating the Safety and effectivenesS in adult KorEaN patients treated with Tolvaptan for management of autosomal domInAnt poLycystic kidney disease (ESSENTIAL): final report
- Hayne Cho Park, Yong Chul Kim, Hyunsuk Kim, Yaerim Kim, Hyun Jin Ryu, Yong Soo Kim, Wookyung Chung, Yong-Lim Kim, Seungyeup Han, Yeonsoon Jung, Ho Sik Shin, Ki Young Na, Kyu Beck Lee, Hyeong Cheon Park, Seung Hyeok Han, Tae-Hyun Yoo, Yeong Hoon Kim, Soo Wan Kim, Kang Wook Lee, Sung Gyun Kim, Chang Hwa Lee, Kyongtae T. Bae, Kook Hwan Oh, Curie Ahn, Yun Kyu Oh
- Kidney Res Clin Pract. 2026;45(2):220-231. Published online September 11, 2024
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Background: Tolvaptan, a selective vasopressin V2 receptor antagonist, was first approved by the Korean Ministry of Food and Drug Safety in 2015 as a treatment option for autosomal dominant polycystic kidney disease (ADPKD). To prescribe tolvaptan safely and effectively, we designed the phase 4 clinical trial among Korean ADPKD patients with chronic kidney disease stages 1 to 3. Methods: A total...
- Patient-reported mental health problems and clinical outcomes in adults with non-dialysis chronic kidney disease
- Jihyun Yang, Young Youl Hyun, Kyu-Beck Lee, Hyo Jin Kim, Sang Heon Suh, Hayne Cho Park, Yun Kyu Oh, Sue Kyung Park, Kook-Hwan Oh
- Kidney Res Clin Pract. 2026;45(2):232-243. Published online October 25, 2024
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Background: Mental health affects well-being and physical health. Among adults with chronic kidney disease (CKD), mental health (MH) problems are common and can induce adverse clinical outcomes. We examined the association between patient-reported MH problems and clinical outcomes in adults with non-dialysis CKD. Methods: This prospective observational study included 1,879 participants from the KNOW-CKD (KoreaN Cohort Study for Outcomes in Patients...
- Original Article s
- Impact of hemodialysis center accreditation on patient mortality: Korean nationwide cohort study
- Hayne Cho Park, Do Hyoung Kim, AJin Cho, Bo Yeon Kim, Miri Lee, Gui Ok Kim, Won-Min Hwang, Jinseog Kim, Dae Joong Kim, Young-Ki Lee
- Kidney Res Clin Pract. 2026;45(2):244-252. Published online September 9, 2024
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Background: Since hemodialysis (HD) patients are prone to various complications and high mortality, they need to be treated in HD units with professional personnel, proper equipment, and facilities. The Korean Society of Nephrology has been conducting an HD unit accreditation program since 2016. This study was performed to evaluate whether a qualified dialysis center (QDC) reduced the mortality of HD...
- Original Articles
- Clinical outcomes of bortezomib-based desensitization in highly sensitized living and deceased donor kidney transplantation
- Hyeran Park, Hanbi Lee, Sang Hun Eum, Ji-Won Min, Hye Eun Yoon, Eun-Jee Oh, Chul Woo Yang, Byung Ha Chung
- Kidney Res Clin Pract. 2026;45(2):253-262. Published online February 19, 2025
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Background: Sensitization acts as an immunological barrier to successful kidney transplantation (KT). We aim to investigate the efficacy and safety of bortezomib-based desensitization (BOZ-DSZ) in both highly sensitized living donor KT (LDKT) and deceased donor KT (DDKT). Methods: We applied BOZ-DSZ to 20 highly sensitized patients—14 LDKT and six DDKT candidates—and analyzed the change in anti-human leukocyte antigen (HLA) antibody,...
- Impact of sex on clinical outcomes according to immunologic risk in spousal donor kidney transplantation
- Seunghyeok Choi, Hanbi Lee, Sang Hun Eum, Ji-Won Min, Hye Eun Yoon, Chul Woo Yang, Byung Ha Chung
- Kidney Res Clin Pract. 2026;45(2):263-273. Published online September 11, 2024
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Background: The aim of this study is to investigate the impact of sex on the clinical outcomes of spousal donor kidney transplantation. Methods: We analyzed 456 spousal donor kidney transplantation recipients and categorized them into standard or high immunological risk groups according to panel-reactive antibody ≥50% or less. There were 366 recipients in the standard-risk group and 89 recipients in...
- Study Protocol
- Study protocol for a consortium linking health medical records, biospecimens, and biosignals in Korean patients with acute kidney injury (LINKA cohort)
- Donghwan Yun, Seung Seok Han, Jeonghwan Lee, Yaerim Kim, Kwangsoo Kim, Kyubok Jin, Ji Eun Kim, Shin Young Ahn, Gang-Jee Ko, Seokwoo Park, Sejoong Kim, Hee-Yeon Jung, Jang-Hee Cho, Sun-Hee Park, Eun Sil Koh, Sungjin Chung, Jung Pyo Lee, Dong Ki Kim, Sung Gyun Kim, Jung Nam An
- Kidney Res Clin Pract. 2026;45(2):274-283. Published online November 11, 2024
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Background: Acute kidney injury (AKI) may transition into acute kidney disease (AKD) or chronic kidney disease (CKD), leading to subacute and chronic deterioration, respectively. Despite extensive research on AKI, a significant gap exists in understanding the specific biomarkers and development of individualized treatments prior to progression to AKD and CKD. Methods: As a consortium linking health medical records, biospecimens, and biosignals,...
- Images in Practice
- Mesangial hyaline degeneration after hematopoietic stem cell transplantation
- Takahisa Kawaguchi, Yutaka Yamaguchi
- Kidney Res Clin Pract. 2026;45(2):284-285. Published online February 27, 2026
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- Correspondence
- Finrenone and sodium-glucose cotransporter 2 inhibitor polypill: how “CONFIDENT” are we?
- Gerry George Mathew
- Kidney Res Clin Pract. 2026;45(2):286-287. Published online December 4, 2025
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