Editorial

July 19, 2022


Using the Mayo Imaging Classification to predict renal outcomes in Korean autosomal dominant polycystic kidney disease patients
Yeonsoon Jung
Kidney Res Clin Pract. 2022;41(4):389-392.

Special Article

July 28, 2022


Korean Society of Nephrology 2022 Recommendations on controversial issues in diagnosis and management of hyponatremia
Yeonhee Lee, Kyung Don Yoo, Seon Ha Baek, et al.
Kidney Res Clin Pract. 2022;41(4):393-411.

Review Article

March 15, 2022


Application of C5 inhibitors in glomerular diseases in 2021
Alexis Werion, Eric Rondeau
Kidney Res Clin Pract. 2022;41(4):412-421.

Review Article

March 29, 2022


Management of autosomal dominant polycystic kidney disease in the era of disease-modifying treatment options
Yeshwanter Radhakrishnan, Parikshit Duriseti, Fouad T. Chebib
Kidney Res Clin Pract. 2022;41(4):422-431.

Original Article

March 3, 2022


Mayo imaging classification is a good predictor of rapid progress among Korean patients with autosomal dominant polycystic kidney disease: results from the KNOW-CKD study
Hayne Cho Park, Yeji Hong, Jeong-Heum Yeon, et al.
Kidney Res Clin Pract. 2022;41(4):432-441.

Original Article

February 23, 2022


Genetic variants of interferon lambda-related genes and chronic kidney disease susceptibility in the Korean population
Jin Ho Kwak, Jin Hyuk Paek, Gyeong Im Yu, et al.
Kidney Res Clin Pract. 2022;41(4):442-451.

Original Article

May 4, 2022


A multicenter, randomized, open-label, comparative, phase IV study to evaluate the efficacy and safety of combined treatment with mycophenolate mofetil and corticosteroids in advanced immunoglobulin A nephropathy
Sang Youb Han, Chan-Young Jung, Sang Ho Lee, et al.
Kidney Res Clin Pract. 2022;41(4):452-461.

Original Article

March 31, 2022


An intradialytic aerobic exercise program ameliorates frailty and improves dialysis adequacy and quality of life among hemodialysis patients: a randomized controlled trial
Sunki Kim, Hye-Ja Park, Dong-Ho Yang
Kidney Res Clin Pract. 2022;41(4):462-472.

Original Article

February 22, 2022


Parathyroidectomy versus cinacalcet in the treatment of tertiary hyperparathyroidism after kidney transplantation: a retrospective study
Suyun Jung, Hyosang Kim, Hyunwook Kwon, et al.
Kidney Res Clin Pract. 2022;41(4):473-481.

Original Article

June 22, 2022


Ambulatory blood pressure trajectories and blood pressure variability in kidney transplant recipients: a comparative study against chronic kidney disease patients
Maria Korogiannou, Marieta Theodorakopoulou, Pantelis Sarafidis, et al.
Kidney Res Clin Pract. 2022;41(4):482-491.

Original Article

July 28, 2022


The Korean Organ Transplantation Registry (KOTRY): an overview and summary of the kidney-transplant cohort
Hee Jung Jeon, Tai Yeon Koo, Man Ki Ju, et al.
Kidney Res Clin Pract. 2022;41(4):492-507.

Study Protocol

April 13, 2022


Efficacy and safety of rapid intermittent bolus compared with slow continuous infusion in patients with severe hypernatremia (SALSA II trial): a study protocol for a randomized controlled trial
Ji Young Ryu, Songuk Yoon, Jeonghwan Lee, et al.
Kidney Res Clin Pract. 2022;41(4):508-520.

Special Article
Korean Society of Nephrology 2022 Recommendations on controversial issues in diagnosis and management of hyponatremia
Yeonhee Lee, Kyung Don Yoo, Seon Ha Baek, Yang Gyun Kim, Hyo Jin Kim, Ji Young Ryu, Jin Hyuk Paek, Sang Heon Suh, Se Won Oh, Jeonghwan Lee, Jong Hyun Jhee, Jin-Soon Suh, Eun Mi Yang, Young Ho Park, Yae Lim Kim, Miyoung Choi, Kook-Hwan Oh, Sejoong Kim
Kidney Res Clin Pract. 2022;41(4):393-411.   Published online July 28, 2022
The Korean Society for Electrolyte and Blood Pressure Research, in collaboration with the Korean Society of Nephrology, has published a clinical practice guideline (CPG) document for hyponatremia treatment. The document is based on an extensive evidence-based review of the diagnosis, evaluation, and treatment of hyponatremia with the multidisciplinary participation of representative experts in hyponatremia with methodologist support for guideline development....
The full-text version of this clinical practice guideline is available on the KRCP website (https://doi.org/10.23876/j.krcp.33.666).
Review Article
Application of C5 inhibitors in glomerular diseases in 2021
Alexis Werion, Eric Rondeau
Kidney Res Clin Pract. 2022;41(4):412-421.   Published online March 15, 2022
The complement pathway is an essential mechanism in innate immunity, but it is also involved in multiple pathologies. For kidney diseases, strong evidence of a dysregulation in the alternative pathway in atypical hemolytic uremic syndrome (aHUS) led to the use of eculizumab, the first anti-C5 inhibitor available in clinical practice. Intensive fundamental research resulted in the development of subsequent new...
Management of autosomal dominant polycystic kidney disease in the era of disease-modifying treatment options
Yeshwanter Radhakrishnan, Parikshit Duriseti, Fouad T. Chebib
Kidney Res Clin Pract. 2022;41(4):422-431.   Published online March 29, 2022
Autosomal dominant polycystic kidney disease (ADPKD) is the reported etiology in 10% of end-stage kidney disease (ESKD) patients and has an estimated prevalence of 12.5 million cases worldwide across all ethnicities. There have been major advancements over the last two decades in understanding the pathogenesis and development of disease-modifying treatment options for ADPKD, culminating in regulatory approval of tolvaptan for...
Original Article
Mayo imaging classification is a good predictor of rapid progress among Korean patients with autosomal dominant polycystic kidney disease: results from the KNOW-CKD study
Hayne Cho Park, Yeji Hong, Jeong-Heum Yeon, Hyunjin Ryu, Yong-Chul Kim, Joongyub Lee, Yeong Hoon Kim, Dong-Wan Chae, WooKyung Chung, Curie Ahn, Kook-Hwan Oh, Yun Kyu Oh
Kidney Res Clin Pract. 2022;41(4):432-441.   Published online March 3, 2022
Background: Mayo imaging classification (MIC) is a useful biomarker to predict disease progression in autosomal dominant polycystic kidney disease (ADPKD). This study was performed to validate MIC in the prediction of renal outcome in a prospective Korean ADPKD cohort and evaluate clinical parameters associated with rapid disease progression. Methods: A total of 178 ADPKD patients were enrolled and prospectively observed...
Genetic variants of interferon lambda-related genes and chronic kidney disease susceptibility in the Korean population
Jin Ho Kwak, Jin Hyuk Paek, Gyeong Im Yu, Seungyeup Han, Woo Yeong Park, Yaerim Kim, Dong Hoon Shin, Kyubok Jin
Kidney Res Clin Pract. 2022;41(4):442-451.   Published online February 23, 2022
Background: Chronic kidney disease (CKD) is a common condition leading to renal dysfunction and is closely related to increased cardiovascular and mortality risk. CKD is an important public health issue, and recent genetic studies have verified common CKD susceptibility variants. This research examines the interrelationship between candidate genes polymorphisms of interferon lambda (IFNL) induction, its signaling pathway, and CKD. Methods:...
A multicenter, randomized, open-label, comparative, phase IV study to evaluate the efficacy and safety of combined treatment with mycophenolate mofetil and corticosteroids in advanced immunoglobulin A nephropathy
Sang Youb Han, Chan-Young Jung, Sang Ho Lee, Dong Won Lee, Sik Lee, Chan-Duck Kim, Bum Soon Choi, Beom Seok Kim
Kidney Res Clin Pract. 2022;41(4):452-461.   Published online May 4, 2022
Background: It remains unclear whether immunosuppressive agents are effective in patients with immunoglobulin A nephropathy (IgAN). We investigated the efficacy of a mycophenolate mofetil (MMF) and corticosteroid combination therapy in patients with advanced IgAN. Methods: We conducted a multicenter, randomized, placebo-controlled, parallel-group study of 48 weeks administration of MMF and corticosteroids in biopsy-proven advanced IgAN patients with estimated glomerular filtration...
An intradialytic aerobic exercise program ameliorates frailty and improves dialysis adequacy and quality of life among hemodialysis patients: a randomized controlled trial
Sunki Kim, Hye-Ja Park, Dong-Ho Yang
Kidney Res Clin Pract. 2022;41(4):462-472.   Published online March 31, 2022
Background: Hemodialysis patients with chronic kidney disease exhibit impaired exercise tolerance and functional decline. Despite the life-saving benefits of adequate dialysis, those declines translate into frailty and deteriorating quality of life (QoL). This study evaluated the effects of an intradialytic aerobic exercise program on frailty, dialysis adequacy, and QoL among hemodialysis patients. Methods: Patients at an university hospital-affiliated hemodialysis center...
Parathyroidectomy versus cinacalcet in the treatment of tertiary hyperparathyroidism after kidney transplantation: a retrospective study
Suyun Jung, Hyosang Kim, Hyunwook Kwon, Sung Shin, Young Hoon Kim, Won Woong Kim, Tae-Yon Sung, Yu-Mi Lee, Ki-Wook Chung, Su-Kil Park, Chung Hee Baek
Kidney Res Clin Pract. 2022;41(4):473-481.   Published online February 22, 2022
Background: Hyperparathyroidism is common in patients with chronic kidney disease with reduced renal function and has been observed after kidney transplantation. The optimal treatment for cases in which hyperparathyroidism persists after kidney transplantation has not been determined. Methods: This retrospective study included 83 patients with tertiary hyperparathyroidism who underwent kidney transplantation between 2000 and 2018 at a single tertiary center...
Ambulatory blood pressure trajectories and blood pressure variability in kidney transplant recipients: a comparative study against chronic kidney disease patients
Maria Korogiannou, Marieta Theodorakopoulou, Pantelis Sarafidis, Maria Eleni Alexandrou, Eva Pella, Efstathios Xagas, Antonis Argyris, Athanase Protogerou, Aikaterini Papagianni, Ioannis N. Boletis, Smaragdi Marinaki
Kidney Res Clin Pract. 2022;41(4):482-491.   Published online June 22, 2022
Background: Hypertension is a major cardiovascular risk factor in both kidney transplant recipients (KTRs) and patients with chronic kidney disease (CKD). Ambulatory blood pressure monitoring (ABPM) is considered the gold-standard method for hypertension management in these subjects. This is the first study evaluating the full ambulatory blood pressure (BP) profile and short-term BP variability (BPV) in KTRs versus CKD patients...
The Korean Organ Transplantation Registry (KOTRY): an overview and summary of the kidney-transplant cohort
Hee Jung Jeon, Tai Yeon Koo, Man Ki Ju, Dong-Wan Chae, Soo Jin Na Choi, Myoung Soo Kim, Jung-Hwa Ryu, Jong Cheol Jeon, Curie Ahn, Jaeseok Yang
Kidney Res Clin Pract. 2022;41(4):492-507.   Published online July 28, 2022
Background: As the need for a nationwide organ-transplant registry emerged, a prospective registry, the Korean Organ Transplantation Registry (KOTRY), was initiated in 2014. Here, we present baseline characteristics and outcomes of the kidney-transplant cohort for 2014 through 2019. Methods: The KOTRY consists of five organ-transplant cohorts (kidney, liver, lung, heart, and pancreas). Data and samples were prospectively collected from transplant...
Study Protocol
Efficacy and safety of rapid intermittent bolus compared with slow continuous infusion in patients with severe hypernatremia (SALSA II trial): a study protocol for a randomized controlled trial

Ji Young Ryu, Songuk Yoon, Jeonghwan Lee, Sumin Baek, You Hwan Jo, Kwang-Pil Ko, Jin-ah Sim, Junhee Han, Sejoong Kim, Seon Ha Baek
Kidney Res Clin Pract. 2022;41(4):508-520.   Published online April 13, 2022
Background: Hypernatremia is a common electrolyte disorder in children and elderly people and has high short-term mortality. However, no high-quality studies have examined the correction rate of hypernatremia and the amount of fluid required for correction. Therefore, in this study, we will compare the efficacy and safety of rapid intermittent bolus (RIB) and slow continuous infusion (SCI) of electrolyte-free solution...

Kidney Research
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Print ISSN: 2211-9132
Online ISSN: 2211-9140


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