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Editorial
January 31, 2023
- Deep learning outperforms kidney organoid experts
- Seyoung Yu, Heon Yung Gee
- Kidney Res Clin Pract. 2023;42(1):1-3.
- Editorial
- Deep learning outperforms kidney organoid experts
- Seyoung Yu, Heon Yung Gee
- Kidney Res Clin Pract. 2023;42(1):1-3. Published online January 31, 2023
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- Review Article
- Cinnamon: an aromatic condiment applicable to chronic kidney disease
- Laís de Souza Gouveia Moreira, Isabela de Souza da Costa Brum, Drielly C. M. de Vargas Reis, Liana Trugilho, Tuany R. Chermut, Marta Esgalhado, Ludmila F. M. F. Cardozo, Peter Stenvinkel, Paul G. Shiels, Denise Mafra
- Kidney Res Clin Pract. 2023;42(1):4-26. Published online January 31, 2023
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Cinnamon, a member of the Lauraceae family, has been widely used as a spice and traditional herbal medicine for centuries and has shown beneficial effects in cardiovascular disease, obesity, and diabetes. However, its effectiveness as a therapeutic intervention for chronic kidney disease (CKD) remains unproven. The bioactive compounds within cinnamon, such as cinnamaldehyde, cinnamic acid, and cinnamate, can mitigate oxidative...
- Pleotropic effects of hypoxia-inducible factor-prolyl hydroxylase domain inhibitors: are they clinically relevant?
- Yu-Hsiang Chou, Szu-Yu Pan, Shuei-Liong Lin
- Kidney Res Clin Pract. 2023;42(1):27-38. Published online November 21, 2022
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Anemia is common in patients with chronic kidney disease (CKD) and is mainly caused by insufficient production of erythropoietin from fibrotic kidney. Because anemia impairs quality of life and overall prognosis, recombinant human erythropoietin-related products (erythropoiesis-stimulating agents, ESAs) have been developed to increase hemoglobin level for decades. However, many safety concerns have been announced regarding the use of ESAs, including...
- Uremic pruritus: pathophysiology, clinical presentation, and treatments
- Mei-Ju Ko, Yu-Sen Peng, Hon-Yen Wu
- Kidney Res Clin Pract. 2023;42(1):39-52. Published online May 4, 2022
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Uremic pruritus is one of the most common and bothersome symptoms in patients with end-stage renal disease. Most patients with uremic pruritus experience a prolonged and relapsing course and significant impairments of quality of life. The pathophysiology of uremic pruritus is not completely understood. A complex interplay among cutaneous biology and the nervous and immune systems has been implicated, with...
- Recent innovations in renal replacement technology and potential applications to transplantation and dialysis patients: a review of current methods
- Calista L Dominy, Ethan B. Shamsian, Kennedy E. Okhawere, Talia G. Korn, Kirolos Meilika, Ketan Badani
- Kidney Res Clin Pract. 2023;42(1):53-62. Published online October 25, 2022
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The current standard of care for patients with end-stage renal disease (ERSD) is a kidney transplant or dialysis when a donor organ isnot available. The growing gap between patients who require a kidney transplant and the availability of donor organs as well as thenegative effects of long-term dialysis, such as infection, limited mobility, and risk of cancer development, drive the...
- Original Article
- Distribution of pathological types and epidemiological characteristics based on kidney biopsy in Northwest China
- Yunlong Qin, Jin Zhao, Xiao Wei, Yuwei Wang, Zixian Yu, Yumeng Zhang, Shiren Sun
- Kidney Res Clin Pract. 2023;42(1):63-74. Published online September 6, 2022
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Background: The spectrum of biopsy-confirmed kidney disease varies with regions and periods. We describe the distribution of pathological types and epidemiological characteristics of kidney diseases in Northwest China due to regional differences in geographical environment, social economy, and dietary habits. Methods: Kidney biopsy cases from 2005 to 2020 in Xijing Hospital were retrospectively analyzed. Pathological characteristics of patients in different...
- Deep learning predicts the differentiation of kidney organoids derived from human induced pluripotent stem cells
- Keonhyeok Park, Jong Young Lee, Soo Young Lee, Iljoo Jeong, Seo-Yeon Park, Jin Won Kim, Sun Ah Nam, Hyung Wook Kim, Yong Kyun Kim, Seungchul Lee
- Kidney Res Clin Pract. 2023;42(1):75-85. Published online September 8, 2022
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Background: Kidney organoids derived from human pluripotent stem cells (hPSCs) contain multilineage nephrogenic progenitor cells and can recapitulate the development of the kidney. Kidney organoids derived from hPSCs have the potential to be applied in regenerative medicine as well as renal disease modeling, drug screening, and nephrotoxicity testing. Despite biotechnological advances, individual differences in morphological and growth characteristics among kidney...
- Weight change and risk of depression in patients with diabetic kidney disease: a nationwide population-based study
- Hong Sang Choi, Bongseong Kim, Kyung-Do Han, Tae Ryom Oh, Sang Heon Suh, Minah Kim, Chang Seong Kim, Eun Hui Bae, Seong Kwon Ma, Soo Wan Kim
- Kidney Res Clin Pract. 2023;42(1):86-97. Published online September 8, 2022
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Background: Several studies have reported that depression is prevalent in patients with diabetes or chronic kidney disease. However, the relationship between weight changes and the risk of depression has not been elucidated in patients with diabetic kidney disease (DKD). Methods: From the Korean National Health Insurance Service database, we selected 67,866 patients with DKD and body weight data from two...
- Comparison of dominant and nondominant C3 deposition in primary glomerulonephritis
- Jiwon Ryu, Eunji Baek, Hyung-Eun Son, Ji-Young Ryu, Jong Cheol Jeong, Sejoong Kim, Ki Young Na, Dong-Wan Chae, Seong Pyo Kim, Su Hwan Kim, Jong Hyun Jhee, Tae Ik Chang, Bum Soon Choi, Ho Jun Chin
- Kidney Res Clin Pract. 2023;42(1):98-108. Published online January 31, 2023
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Background: Alternative complement pathway dysregulation plays a key role in glomerulonephritis (GN) and is associated with C3 deposition. Herein, we examined pathological and clinical differences between cases of primary GN with C3-dominant (C3D-GN) and nondominant (C3ND-GN) deposition. Methods: We extracted primary GN data from the Korean GlomeruloNEphritis sTudy (KoGNET). C3D-GN was defined as C3 staining two grades greater than C1q,...
- Hemodialysis facility star rating affects mortality in chronic hemodialysis patients: a longitudinal observational cohort study
- Hayne Cho Park, Hyung Yun Choi, Do Hyoung Kim, AJin Cho, Young Eun Kwon, Dong-Ryeol Ryu, Ki Hwa Yang, Eun Mi Won, Ji Hyeon Shin, Jinseog Kim, Young-Ki Lee
- Kidney Res Clin Pract. 2023;42(1):109-116. Published online September 13, 2022
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Background: Many countries have their own hemodialysis (HD) quality assurance programs and star rating systems for HD facilities. However, the effects of HD quality assurance programs on patient mortality are not well understood. Therefore, in the present study, the effects of the Korean HD facility star rating on patient mortality in maintenance HD patients were evaluated. Methods: This longitudinal, observational...
- Impact of needle type on substitution volume during online hemodiafiltration: plastic cannulae versus metal needles
- AJin Cho, Hayne Cho Park, Do Hyoung Kim, Han Byul Choi, Gi Hyun Song, Hyunsuk Kim, Seok-hyung Kim, Gwangho Choi, Jwa-Kyung Kim, Young Rim Song, Jong-Woo Yoon, Young-Ki Lee
- Kidney Res Clin Pract. 2023;42(1):117-126. Published online October 25, 2022
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Background: Plastic cannulae have attracted increasing interest as an alternative to traditional metal needles with the aim of reducing cannulation-related complications. We investigated whether the substitution volumes during hemodiafiltration differ using these two types of needles in dialysis patients. Methods: An intervention study involving 26 hemodialysis patients was conducted in Korea between March and September in 2021. Patients first received...
- Optimal peritoneal fluid white blood cell count for diagnosis of peritonitis in peritoneal dialysis patients
- Margarita Kunin, Sharon Mini, Nabil Abu-Amer, Pazit Beckerman
- Kidney Res Clin Pract. 2023;42(1):127-137. Published online September 14, 2022
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Background: The diagnosis of peritonitis among peritoneal dialysis (PD) patients is based on clinical presentation, dialysis effluent white blood cell (WBC) count, and dialysis effluent culture. Peritoneal fluid WBC count is very important in the initial diagnosis of peritonitis. The purpose of this work was to determine the optimal number of peritoneal WBCs with different clinical presentations at admission to...
- The comparative efficacy and safety of basiliximab and antithymocyte globulin in deceased donor kidney transplantation: a multicenter cohort study
- Su Yeon Hong, Young Soo Kim, Kyubok Jin, Seungyeup Han, Chul Woo Yang, Byung Ha Chung, Woo Yeong Park
- Kidney Res Clin Pract. 2023;42(1):138-148. Published online January 31, 2023
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Background: Generally, an induction agent is chosen based on the conditions of the deceased donor and the recipient. Antithymocyte globulin (ATG) is preferred in relatively high-risk conditions. No clear evidence indicates which induction agent is safer or more efficient for deceased donor kidney transplantation (DDKT). This study compares the efficacy and safety of basiliximab (BSX) and ATG according to donor...
- Images in Practice
- Malakoplakia in the recipient’s native kidney after kidney transplantation
- Yeojin Boo, Hyunee Yim, Jun Bae Bang
- Kidney Res Clin Pract. 2023;42(1):149-151. Published online January 13, 2023
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