Editorial

May 28, 2024


Unveiling the genetic architecture of kidney function in the Korean population
Sehoon Park
Kidney Res Clin Pract. 2024;43(3):257-259.

Editorial

May 28, 2024


Does the primary cilium elongation play a role in urine concentration?
Tae-Hwan Kwon
Kidney Res Clin Pract. 2024;43(3):260-262.

Special Article

May 28, 2024


Trends in clinical outcomes of older hemodialysis patients: data from the 2023 Korean Renal Data System (KORDS)
Hyunglae Kim, Seon A Jeong, Kyeong Min Kim, et al.
Kidney Res Clin Pract. 2024;43(3):263-273.

Review Article

February 6, 2024


Urinary podocyte markers in diabetic kidney disease
Chuanlei Li, Cheuk-Chun Szeto
Kidney Res Clin Pract. 2024;43(3):274-286.

Review Article

March 18, 2024


School urinary screening program in Japan: history, outcomes, perspectives
Masataka Honda, Takeshi Yanagihara, Yoshimitsu Gotoh
Kidney Res Clin Pract. 2024;43(3):287-298.

Original Article

November 3, 2023


Genome-wide association study and fine-mapping on Korean biobank to discover renal trait-associated variants
Dong-Jin Lee, Jong-Seok Moon, Dae Kwon Song, et al.
Kidney Res Clin Pract. 2024;43(3):299-312.

Original Article

November 7, 2023


High water intake induces primary cilium elongation in renal tubular cells
Min Jung Kong, Sang Jun Han, Sung Young Seu, et al.
Kidney Res Clin Pract. 2024;43(3):313-325.

Original Article

February 19, 2024


Anti-SARS-CoV-2 spike antibody response to the third dose of BNT162b2 mRNA COVID-19 vaccine and associated factors in Japanese hemodialysis patients
Keiji Hirai, Masako Shimotashiro, Toshiaki Okumura, et al.
Kidney Res Clin Pract. 2024;43(3):326-336.

Original Article

February 8, 2024


Mortality associated with the neutrophil-lymphocyte ratio in septic acute kidney injury requiring continuous renal replacement therapy
Jinwoo Lee, Jeongin Song, Seong Geun Kim, et al.
Kidney Res Clin Pract. 2024;43(3):337-347.

Original Article

September 1, 2023


Clinical relevance of blood urea nitrogen to serum albumin ratio for predicting bacteremia in very young children with febrile urinary tract infection
Hyesun Hyun, Yeon hee Lee, Na Yoon Kang, et al.
Kidney Res Clin Pract. 2024;43(3):348-357.

Original Article

December 18, 2023


Association between hearing loss and physical performance in patients on maintenance hemodialysis
Weifeng Fan, Xiaojing Zhong, Qing Wu, et al.
Kidney Res Clin Pract. 2024;43(3):358-368.

Original Article

January 23, 2024


Efficacy and cost-effectiveness of darbepoetin alfa once every 4 weeks versus continuous erythropoietin receptor activator once every 4 weeks for anemia correction in patients with chronic kidney disease not on dialysis
Geo Neul Park, Kyung Ho Lee, Ji Eun Moon, et al.
Kidney Res Clin Pract. 2024;43(3):369-380.

Original Article

March 18, 2024


Triglyceride-glucose index is an independent predictor of coronary artery calcification progression in patients with chronic kidney disease
Ye Eun Ko, Hyung Woo Kim, Jung Tak Park, et al.
Kidney Res Clin Pract. 2024;43(3):381-390.

Editorials
Unveiling the genetic architecture of kidney function in the Korean population
Sehoon Park
Kidney Res Clin Pract. 2024;43(3):257-259.   Published online May 28, 2024
Does the primary cilium elongation play a role in urine concentration?
Tae-Hwan Kwon
Kidney Res Clin Pract. 2024;43(3):260-262.   Published online May 28, 2024
Special Article
Trends in clinical outcomes of older hemodialysis patients: data from the 2023 Korean Renal Data System (KORDS)
Hyunglae Kim, Seon A Jeong, Kyeong Min Kim, Sun Deuk Hwang, Sun Ryoung Choi, Hajeong Lee, Ji Hyun Kim, Su Hyun Kim, Tae Hee Kim, Ho-Seok Koo, Chang-Yun Yoon, Kiwon Kim, Seon Ho Ahn, Hye Eun Yoon, Yong Kyun Kim, Tae Hyun Ban, Yu Ah Hong
Kidney Res Clin Pract. 2024;43(3):263-273.   Published online May 28, 2024
With an increasing aging population, the mean age of patients with end-stage kidney disease (ESKD) is globally increasing. However, the current clinical status of elderly patients undergoing hemodialysis (HD) is rarely reported in Korea. The current study analyzed the clinical features and trends of older patients undergoing HD from the Korean Renal Data System (KORDS) database. The patients were divided...
Review Articles
Urinary podocyte markers in diabetic kidney disease
Chuanlei Li, Cheuk-Chun Szeto
Kidney Res Clin Pract. 2024;43(3):274-286.   Published online February 6, 2024
Podocytes are involved in maintaining kidney function and are a major focus of research on diabetic kidney disease (DKD). Urinary biomarkers derived from podocyte fragments and molecules have been proposed for the diagnosis and monitoring of DKD. Various methods have been used to detect intact podocytes and podocyte-derived microvesicles in urine, including centrifugation, visualization, and molecular quantification. Quantification of podocyte-specific...
School urinary screening program in Japan: history, outcomes, perspectives
Masataka Honda, Takeshi Yanagihara, Yoshimitsu Gotoh
Kidney Res Clin Pract. 2024;43(3):287-298.   Published online March 18, 2024
In Japan, pediatric urinary screening in schools for asymptomatic hematuria and proteinuria began in 1974 and has been very successful in detecting asymptomatic kidney diseases at an early stage. While the American Academy of Pediatrics recommended discontinuing urinalysis as a public health service in 2007, urinary screening in Japan has proven extremely successful in reducing the incidence of kidney failure...
Original Articles
Genome-wide association study and fine-mapping on Korean biobank to discover renal trait-associated variants

Dong-Jin Lee, Jong-Seok Moon, Dae Kwon Song, Yong Seok Lee, Dong-Sub Kim, Nam-Jun Cho, Hyo-Wook Gil, Eun Young Lee, Samel Park
Kidney Res Clin Pract. 2024;43(3):299-312.   Published online November 3, 2023
Background: Chronic kidney disease is a significant health burden worldwide, with increasing incidence. Although several genome- wide association studies (GWAS) have investigated single nucleotide polymorphisms (SNP) associated with kidney trait, most studies were focused on European ancestry. Methods: We utilized clinical and genetic information collected from the Korean Genome and Epidemiology Study (KoGES). Results: More than five million SNPs from...
High water intake induces primary cilium elongation in renal tubular cells

Min Jung Kong, Sang Jun Han, Sung Young Seu, Ki-Hwan Han, Joshua H. Lipschutz, Kwon Moo Park
Kidney Res Clin Pract. 2024;43(3):313-325.   Published online November 7, 2023
Background: The primary cilium protrudes from the cell surface and functions as a mechanosensor. Recently, we found that water intake restriction shortens the primary cilia of renal tubular cells, and a blockage of the shortening disturbs the ability of the kidneys to concentrate urine. Here, we investigate whether high water intake (HWI) alters primary cilia length, and if so, what...
Anti-SARS-CoV-2 spike antibody response to the third dose of BNT162b2 mRNA COVID-19 vaccine and associated factors in Japanese hemodialysis patients

Keiji Hirai, Masako Shimotashiro, Toshiaki Okumura, Susumu Ookawara, Yoshiyuki Morishita
Kidney Res Clin Pract. 2024;43(3):326-336.   Published online February 19, 2024
Background: We assessed the anti-SARS-CoV-2 spike antibody response to the third dose of BNT162b2 mRNA COVID-19 vaccine in Japanese hemodialysis patients and determined factors associated with the anti-SARS-CoV-2 spike antibody titer after the third dose of COVID-19 vaccine. Methods: Overall, 64 patients were enrolled in this single-center, prospective, longitudinal study. Anti-SARS-CoV-2 spike antibody titers were compared between hemodialysis patients and...
Mortality associated with the neutrophil-lymphocyte ratio in septic acute kidney injury requiring continuous renal replacement therapy

Jinwoo Lee, Jeongin Song, Seong Geun Kim, Donghwan Yun, Min Woo Kang, Dong Ki Kim, Kook-Hwan Oh, Kwon Wook Joo, Yon Su Kim, Seung Seok Han, Yong Chul Kim
Kidney Res Clin Pract. 2024;43(3):337-347.   Published online February 8, 2024
Background: Sepsis is an important cause of acute kidney injury in intensive care unit patients, accounting for 15% to 20% of renal replacement therapy prescriptions. The neutrophil-lymphocyte ratio (NLR), a marker of systemic inflammation and immune response, was previously associated with the mortality rate in multiple conditions. Herein, we aimed to examine how the NLR relates to the mortality rate...
Clinical relevance of blood urea nitrogen to serum albumin ratio for predicting bacteremia in very young children with febrile urinary tract infection

Hyesun Hyun, Yeon hee Lee, Na Yoon Kang, Jin-Soon Suh
Kidney Res Clin Pract. 2024;43(3):348-357.   Published online September 1, 2023
Background: Urinary tract infections (UTIs) are one of the most common bacterial infections in febrile children and a common cause of hospitalization, especially in very young children. We examined the clinical characteristics and predictive factors of concomitant bacteremia in pediatric patients with febrile UTI aged ≤24 months. Methods: This retrospective multicenter study reviewed medical data from 2,141 patients from three...
Association between hearing loss and physical performance in patients on maintenance hemodialysis

Weifeng Fan, Xiaojing Zhong, Qing Wu, Lihong Zhang, Zhenhao Yang, Yong Gu, Qi Guo, Xiaoyu Chen, Chen Yu, Kun Zhang, Wei Ding, Hualin Qi, Junli Zhao, Liming Zhang, Suhua Zhang, Jianying Niu
Kidney Res Clin Pract. 2024;43(3):358-368.   Published online December 18, 2023
Background: The correlation between hearing loss (HL) and physical performance in patients receiving maintenance hemodialysis (MHD) remains poorly investigated. This study explored the association between HL and physical performance in patients on MHD. Methods: This multicenter cross-sectional study was conducted between July 2020 and April 2021 in seven hemodialysis centers in Shanghai and Suzhou, China. The hearing assessment was performed...
Efficacy and cost-effectiveness of darbepoetin alfa once every 4 weeks versus continuous erythropoietin receptor activator once every 4 weeks for anemia correction in patients with chronic kidney disease not on dialysis

Geo Neul Park, Kyung Ho Lee, Ji Eun Moon, Soo Jeong Choi, Moo Yong Park, Jin Kuk Kim, Byung Chul Yu
Kidney Res Clin Pract. 2024;43(3):369-380.   Published online January 23, 2024
Background: For anemia management in patients with chronic kidney disease not on dialysis, darbepoetin alfa (DA), which has a shorter half-life but is more inexpensive than continuous erythropoietin receptor activator (CERA), is preferred in Korea. This study evaluated the efficacy, safety, and cost-effectiveness of once-in-4-weeks DA compared with once-in-4-weeks CERA in patients with chronic kidney disease not on dialysis. Methods:...
Triglyceride-glucose index is an independent predictor of coronary artery calcification progression in patients with chronic kidney disease

Ye Eun Ko, Hyung Woo Kim, Jung Tak Park, Seung Hyeok Han, Shin-Wook Kang, Suah Sung, Kyu-Beck Lee, Joongyub Lee, Kook-Hwan Oh, Tae-Hyun Yoo
Kidney Res Clin Pract. 2024;43(3):381-390.   Published online March 18, 2024
Background: Coronary artery calcification (CAC) is highly prevalent in patients with chronic kidney disease (CKD) and is associated with major adverse cardiovascular events and metabolic disturbances. The triglyceride-glucose index (TyGI), a novel surrogate marker of metabolic syndrome and insulin resistance, is associated with CAC in the general population and in patients with diabetes. This study investigated the association between the...
APCN_KSN_2024

Kidney Research
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Clinical Practice

Print ISSN: 2211-9132
Online ISSN: 2211-9140


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