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Editorial
September 7, 2021
- A novel role of copeptin as a biomarker for the prediction of treatment response in hyponatremia
- Sang Heon Suh, Soo Wan Kim
- Kidney Res Clin Pract. 2021;40(3):329-331.
- Editorial
- A novel role of copeptin as a biomarker for the prediction of treatment response in hyponatremia
- Sang Heon Suh, Soo Wan Kim
- Kidney Res Clin Pract. 2021;40(3):329-331. Published online September 7, 2021
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- Who is the winner, pre-, post-, or mixed-dilution hemodiafiltration?
- Hayne Cho Park, Young-Ki Lee
- Kidney Res Clin Pract. 2021;40(3):332-334. Published online September 7, 2021
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- Review Article
- Intestinal microbiota and kidney diseases
- Myung-Gyu Kim, Jihyun Yang, Sang-Kyung Jo
- Kidney Res Clin Pract. 2021;40(3):335-343. Published online June 9, 2021
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Large microbial communities reside in the gut as an endogenous organ and interact with the host physiology through symbiotic relationships, affecting health. Recent advances in high-throughput sequencing techniques have made it possible to better understand these complex microbial communities and their effects on hosts. Animal and clinical studies have provided considerable evidence to show that the microbiota plays an important...
- Nephrotoxicity of cancer therapeutic drugs: Focusing on novel agents
- Min Hee Hong
- Kidney Res Clin Pract. 2021;40(3):344-354. Published online July 8, 2021
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Kidney injury caused by anticancer agents is a common problem that can interfere with and affect the dose intensity of anticancer therapy, thus restricting patient survival. Recent advances in targeted and immunotherapeutic agents have transformed the landscape of medical oncology, and these agents have been widely employed in clinical practice. While typically associated with favorable toxicity profiles, several novel anticancer...
- Kidney transplantation in highly sensitized recipients
- Yohan Park, Eun Jeong Ko, Byung Ha Chung, Chul Woo Yang
- Kidney Res Clin Pract. 2021;40(3):355-370. Published online June 25, 2021
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In kidney transplantation (KT), overcoming donor shortage is particularly challenging in patients with preexisting donor-specific antibodies (DSAs) against human leukocyte antigen (HLA), called HLA-incompatible KT (HLAi KT), carrying the risk of rejection and allograft loss. Thus, it is necessary to accurately evaluate the degree of sensitization before HLAi KT, and undertake appropriate pretreatment strategies. To determine the degree of sensitization,...
- Original Article
- Association between copeptin levels and treatment responses to hypertonic saline infusion in patients with symptomatic hyponatremia: a prospective cohort study
- Suryeong Go, Sejoong Kim, Hyung-Eun Son, Ji-Young Ryu, Huijin Yang, Sun Ryoung Choi, Jang-Won Seo, You Hwan Jo, Ja-Ryong Koo, Seon Ha Baek
- Kidney Res Clin Pract. 2021;40(3):371-382. Published online July 8, 2021
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Background: Copeptin is secreted in equimolar amounts as arginine vasopressin, main hormone regulating body fluid homeostasis. A recent study reported a copeptin-based classification of osmoregulatory defects in syndromes of inappropriate antidiuresis that may aid in prediction of therapeutic success. We investigated usefulness of copeptin for differentiating etiologies of hyponatremia and predicting efficacy and safety of hypertonic saline treatment in hyponatremic...
- Urinary exosomal microRNA profiling in type 2 diabetes patients taking dipeptidyl peptidase-4 inhibitor compared with sulfonylurea
- Nam-Jun Cho, Dae-Yeon Kim, Soon Hyo Kwon, Tae Won Ha, Hyun Kyu Kim, Man Ryul Lee, Sung Wan Chun, Samel Park, Eun-young Lee, Hyo-Wook Gil
- Kidney Res Clin Pract. 2021;40(3):383-391. Published online July 7, 2021
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Background: Dipeptidyl peptidase-4 (DPP-4) inhibitor has been reported to have kidney-protective benefits. To elucidate how antidiabetic agents prevent diabetic kidney disease progression, it is important to investigate their effect on the kidney environment in type 2 diabetes mellitus (DM) patients. Herein, we investigated the expression pattern of urinary exosome-derived microRNA (miRNA) in patients taking a combination of DPP-4 inhibitor and...
- Effect of pravastatin on erythrocyte membrane fatty acid contents in patients with chronic kidney disease
- Su Mi Lee, Young Ki Son, Seong Eun Kim, Yeong Hoon Kim, Yongsoon Park, Won Suk An
- Kidney Res Clin Pract. 2021;40(3):392-400. Published online May 26, 2021
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Background: Statin treatment has decreased the risk of cardiovascular events in patients with chronic kidney disease (CKD). Erythrocyte membrane oleic acid level is higher in patients with acute coronary syndrome. This study aimed to evaluate the effect of pravastatin on the erythrocyte membrane fatty acid (FA) contents in patients with CKD. Methods: Sixty-two patients were enrolled from January 2017 to March...
- Mortality predictors in critically ill patients with acute kidney injury requiring continuous renal replacement therapy
- Kristianne Rachel P. Medina-Liabres, Jong Cheol Jeong, Hyung Jung Oh, Jung Nam An, Jung Pyo Lee, Dong Ki Kim, Dong-Ryeol Ryu, Sejoong Kim
- Kidney Res Clin Pract. 2021;40(3):401-410. Published online July 5, 2021
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Background: Because of high cost of continuous renal replacement therapy (CRRT) and the high mortality rate among severe acute kidney injury patients, careful identification of patients who will benefit from CRRT is warranted. This study determined factors associated with mortality among critically ill patients requiring CRRT. Methods: This was a retrospective observational study of 414 patients admitted to the intensive...
- Hyperuricemia is a risk factor for the progression to end-stage renal disease in minimal change disease
- Su Hyun Song, Tae Ryom Oh, Hong Sang Choi, Chang Seong Kim, Dong Ryeol Ryu, Sung Gyun Kim, Sun-Hee Park, Seong Kwon Ma, Soo Wan Kim, Eun Hui Bae
- Kidney Res Clin Pract. 2021;40(3):411-418. Published online September 9, 2021
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Background: Minimal change disease (MCD) is one of the most common causes of nephrotic syndrome worldwide. Hyperuricemia increases the end-stage renal disease (ESRD) risk in glomerulonephritis. In this study, we aimed to determine the effect of high serum uric acid levels on the progression to ESRD in MCD. Methods: A total of 800 patients diagnosed with MCD by kidney biopsy were...
- Preexisting comorbidities are associated with the mortality rate as well as the predialysis adverse events in incident dialysis patients
- Min-Jeong Lee, Inwhee Park, Heungsoo Kim, Gyu-Tae Shin, Jong Cheol Jeong
- Kidney Res Clin Pract. 2021;40(3):419-431. Published online August 13, 2021
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Background: Optimal estimated glomerular filtration rate (eGFR) to start maintenance dialysis is controversial. Observational studies have reported that initiation of dialysis at high eGFRs is associated with worse postdialysis survival. Methods: We retrospectively investigated 1,038 incident dialysis patients who started maintenance dialysis during 2010-2015. Patients were assessed for comorbidities and adverse events during the transitional period of dialysis initiation. Patients...
- Blood pressure prior to percutaneous coronary intervention is associated with the risk of end-stage renal disease: a nationwide population based-cohort study
- Eun Hui Bae, Sang Yup Lim, Bongseong Kim, Kyung-Do Han, Tae Ryom Oh, Hong Sang Choi, Chang Seong Kim, Seong Kwon Ma, Soo Wan Kim
- Kidney Res Clin Pract. 2021;40(3):432-444. Published online July 2, 2021
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Background: Hypertension is the most important modifiable risk factor for mortality and morbidity in chronic kidney disease and coronary artery syndrome. The effect of hypertension prior to percutaneous coronary intervention (PCI) on the development of end-stage renal disease (ESRD) is unknown. Methods: We used nationally representative data from the Korean National Health Insurance System—140,164 subjects were enrolled during 2010–2015; they...
- Mixed- versus predilution hemodiafiltration effects on convection volume and small and middle molecule clearance in hemodialysis patients: a prospective randomized controlled trial
- Kyoung Sook Park, Ea Wha Kang, Tae Ik Chang, Wonji Jo, Jung Tak Park, Tae-Hyun Yoo, Shin-Wook Kang, Seung Hyeok Han
- Kidney Res Clin Pract. 2021;40(3):445-456. Published online July 30, 2021
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Background: The use of newly developed mixed-dilution hemodiafiltration (HDF) can supplement the weaknesses of pre- and postdilution HDF. However, it is unclear whether mixed-HDF performs well compared to predilution HDF. Methods: We conducted a prospective, open-labeled, randomized controlled trial from two hemodialysis centers in Korea. Between January 2017 and September 2019, 60 patients who underwent chronic hemodialysis were randomly assigned...
- Effect of Phoxilium on prognostic predictors in patients undergoing continuous venovenous hemodiafiltration
- Da Woon Kim, Hyo Jin Kim, Jin Mi Kim, You Hyun Jeon, Miyeun Han, Eun Young Seong, Sang Heon Song
- Kidney Res Clin Pract. 2021;40(3):457-471. Published online July 19, 2021
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Background: Phosphorus-containing dialysis solution is used to prevent hypophosphatemia in patients undergoing continuous venovenous hemodiafiltration (CVVHDF). This study evaluated the effect of phosphorus-containing dialysis solution on mortality in patients undergoing CVVHDF based on changes in phosphorus and red cell distribution width-coefficient of variation (RDW-CV) levels. Methods: We included 272 patients with acute kidney injury (AKI) who underwent CVVHDF at the medical...
- Evolving outcomes of peritoneal dialysis: secular trends at a single large center over three decades
- Minjung Kang, Yae Lim Kim, Eunjeong Kang, Hyunjin Ryu, Yong Chul Kim, Dong Ki Kim, Hajeong Lee, Seung Seok Han, Kwon-Wook Joo, Yon Su Kim, Curie Ahn, Kook-Hwan Oh
- Kidney Res Clin Pract. 2021;40(3):472-483. Published online July 1, 2021
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Background: Peritoneal dialysis (PD) is improving as a renal replacement therapy for end-stage renal disease (ESRD) patients. We analyzed the main outcomes of PD over the last three decades at a single large-scale PD center with an established high-quality care system. Methods: As a retrospective cohort study, we included participants (n = 1,203) who began PD between 1990 and 2019....
- Comparison of normal saline solution with low-chloride solutions in renal transplants: a meta-analysis
- Abdullah Jahangir, Syeda Sahra, Muhammad Rafay Khan Niazi, Fasih Sami Siddiqui, Muhammad Yasir Anwar, Ahmad Jahangir, Elie J. El-Charabaty
- Kidney Res Clin Pract. 2021;40(3):484-495. Published online June 8, 2021
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Background: Normal saline solution (NSS) has been the fluid of choice for renal transplant patients, but it can lead to hyperchloremic acidosis and hyperkalemia. This study was performed to compare the safety profile of low-chloride solutions with that of NSS in renal transplant patients. Methods: We conducted a systemic review search on PubMed, Embase, and the Central Cochrane Registry. Randomized clinical...
- Correspondence
- BK polyomavirus infection following COVID-19 infection in renal transplant recipients: a single-center experience
- Hari Shankar Meshram, Vivek B. Kute, Sanshriti Chauhan
- Kidney Res Clin Pract. 2021;40(3):496-500. Published online August 6, 2021
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- Fighting COVID-19: The role of a COVID-19 Task Force Team
- Hayne Cho Park, Young-Ki Lee, Jang-Hee Cho, Sang-Ho Lee, Dong Ki Kim, Seong Nam Kim, Chul-Woo Yang
- Kidney Res Clin Pract. 2021;40(3):501-504. Published online August 31, 2021
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