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Editorial
September 7, 2021
- A novel role of copeptin as a biomarker for the prediction of treatment response in hyponatremia
- Sang Heon Suh, Soo Wan Kim
- Kidney Res Clin Pract. 2021;40(3):329-331.
- Original Articles
- Modeling of endothelial cell dysfunction using human induced pluripotent stem cells derived from patients with end-stage renal disease
- Kyoung Woon Kim, Yoo Jin Shin, Bo-Mi Kim, Sheng Cui, Eun Jeong Ko, Sun Woo Lim, Chul Woo Yang, Byung Ha Chung
- Received December 7, 2020 Accepted July 6, 2021
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Background: Endothelial cell (EC) dysfunction is a frequent feature in patients with end-stage renal disease (ESRD). The aim of this study was to generate human induced pluripotent stem cells, differentiate ECs (hiPSC-ECs) from patients with ESRD, and appraise the usefulness of hiPSC-ECs as a model to investigate EC dysfunction. Methods: We generated hiPSCs using peripheral blood mononuclear cells (PBMCs) isolated... -
DOI: https://doi.org/10.23876/j.krcp.20.252 [Epub ahead of print]
- Metabolic risks in living kidney donors in South Korea
- Eunjeong Kang, Jina Park, Hyo Jeong Kim, Sehoon Park, Minsu Park, Yaerim Kim, Kwangsoo Kim, Sang Min Park, Dong-Wan Chae, Ho Jun Chin, Jung Pyo Lee, Sik Lee, Soo Wan Kim, Jang-Hee Cho, Miyeun Han, Yong Chul Kim, Yon Su Kim, Insun Choi, Hajeong Lee
- Received December 26, 2020 Accepted May 27, 2021
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Background: Considering the growing prevalence of Western lifestyles and related chronic diseases occurring in South Korea, this study aimed to explore the progression of metabolic risk factors in living kidney donors compared to a control group. Methods: This study enrolled living kidney donors from seven hospitals from 1982 to 2016. The controls were individuals that voluntarily received health check-ups from... -
DOI: https://doi.org/10.23876/j.krcp.20.271 [Epub ahead of print]
- Renal outcomes of laparoscopic versus open surgery in patients with rectal cancer: a propensity score analysis
- Jin Hyuk Paek, Sung Il Kang, Jiwon Ryu, Sung Yoon Lim, Ji Young Ryu, Hyung Eun Son, Jong Cheol Jeong, Ho Jun Chin, Ki Young Na, Dong-Wan Chae, Sung-Bum Kang, Sejoong Kim
- Received January 1, 2021 Accepted June 27, 2021
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Background: A laparoscopic approach is widely used in abdominal surgery. Although several studies have compared surgical and oncological outcomes between laparoscopic surgery (LS) and open surgery (OS) in rectal cancer patients, there have been few studies on postoperative renal outcomes. Methods: We conducted a retrospective cohort study involving 1,633 patients who underwent rectal cancer surgery between 2003 and 2017.... -
DOI: https://doi.org/10.23876/j.krcp.21.002 [Epub ahead of print]
- Hepatocyte growth factor and soluble cMet levels in plasma are prognostic biomarkers of mortality in patients with severe acute kidney injury
- Lilin Li, Jung Nam An, Jeonghwan Lee, Dong Jin Shin, Shi Mao Zhu, Jin Hyuk Kim, Dong Ki Kim, Dong-Ryeol Ryu, Sejoong Kim, Jung Pyo Lee
- Received December 15, 2020 Accepted June 7, 2021
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Background: Hepatocyte growth factor (HGF)/cMet pathway is necessary for repair and regeneration following acute kidney injury (AKI). We evaluated the clinical potential of plasma HGF and soluble cMet as prognostic biomarkers for severe AKI requiring continuous renal replacement therapy (CRRT). Methods: One hundred thirty-six patients with severe AKI who participated in the VENUS (volume management under body composition monitoring in critically... -
DOI: https://doi.org/10.23876/j.krcp.20.258 [Epub ahead of print]
- Effects of the route of erythropoietin administration on hemoglobin variability and cardiovascular events in hemodialysis patients
- Do Hyoung Kim, Young-Ki Lee, Juhee Kim, Hayne Cho Park, Kyu Sang Yun, AJin Cho, Jong-Woo Yoon, Ja-Ryong Koo, Jung-Woo Noh
- Received December 17, 2020 Accepted June 6, 2021
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Introduction: Despite the routine use of erythropoietin in hemodialysis patients to correct anemia, its administration route’s effects on hemoglobin variability and cardiovascular events remain elusive. Herein, we determined different erythropoietin administration routes’ effects on hemoglobin variability in hemodialysis patients and the associated factors of hemoglobin variability and cardiovascular events. Methods: This is a post hoc analysis of a prospective, controlled, randomized,... -
DOI: https://doi.org/10.23876/j.krcp.20.260 [Epub ahead of print]
- Characteristics of pediatric rhabdomyolysis and the associated risk factors for acute kidney injury: a retrospective multicenter study in Korea
- Sukdong Yoo, Min Hyun Cho, Hee Sun Baek, Ji Yeon Song, Hye Sun Lee, Eun Mi Yang, Kee Hwan Yoo, Su Jin Kim, Jae Il Shin, Keum Hwa Lee, Tae-Sun Ha, Kyung Mi Jang, Jung Won Lee, Kee Hyuck Kim, Heeyeon Cho, Mee Jeong Lee, Jin-Soon Suh, Kyoung Hee Han, Hye Sun Hyun, Il-Soo Ha, Hae Il Cheong, Hee Gyung Kang, Mee Kyung Namgoong, Hye-Kyung Cho, Jae-Hyuk Oh, Sang Taek Lee, Kyo Sun Kim, Joo Hoon Lee, Young Seo Park, Seong Heon Kim
- Received March 3, 2021 Accepted June 20, 2021
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Background: The clinical features of pediatric rhabdomyolysis differ from those of the adults with rhabdomyolysis; however, multicenter studies are lacking. This study aimed to investigate the characteristics of pediatric rhabdomyolysis and reveal the risk factors for acute kidney injury (AKI) in such cases. Methods: This retrospective study analyzed the medical records of children and adolescents diagnosed with rhabdomyolysis at 23 hospitals... -
DOI: https://doi.org/10.23876/j.krcp.21.051 [Epub ahead of print]
- Clinical outcomes and prognostic factors of mortality in liver cirrhosis patients on continuous renal replacement therapy in two tertiary hospitals in Korea
- You Hyun Jeon, Il Young Kim, Gum Sook Jang, Sang Heon Song, Eun Young Seong, Dong Won Lee, Soo Bong Lee, Hyo Jin Kim
- Received February 6, 2021 Accepted May 29, 2021
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Background: Data on liver cirrhosis (LC) patients undergoing continuous renal replacement therapy (CRRT) are lacking despite the dismal prognosis. We therefore evaluated clinical characteristics and predictive factors related to mortality in LC patients undergoing CRRT. Methods: We performed a retrospective observational study at two tertiary hospitals in Korea. A total of 229 LC patients who underwent CRRT were analyzed. Patients were... -
DOI: https://doi.org/10.23876/j.krcp.21.033 [Epub ahead of print]
- Neutrophil extracellular traps and heparin-induced antibodies contribute to vascular access thrombosis in hemodialysis patients
- Hoi Woul Lee, Jung Nam An, Hyung Seok Lee, Young Rim Song, Hyung Jik Kim, Sung Gyun Kim, Jwa-Kyung Kim
- Received April 12, 2021 Accepted June 3, 2021
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Background: Anti-heparin/platelet factor 4 (PF4) antibodies may trigger severe thrombotic complications in hemodialysis (HD) patients. Tetrameric PF4 has a high affinity for extracellular DNA, which is a key component of neutrophil extracellular traps (NETs); therefore, the interactions between anti-heparin/PF4 antibodies and NETs can contribute to prothrombotic events. This prospective observational study included both incident and maintenance HD (MHD) patients. Methods:... -
DOI: https://doi.org/10.23876/j.krcp.21.080 [Epub ahead of print]
