| A Case of Castleman's Disease with Kidney Involvement |
| Ji Eon Won, M.D.1, Seon Ju Jeong, M.D.1, Jai Hyeun Cho, M.D.1 Je Yeol Kim, M.D.1, Eun Jeong Kim, M.D.1, 3, Hyeong Jik Kim, M.D.1, 3 Young Rim Song, M.D.3, Eun Sook Nam, M.D.2, 3 and Seong Gyun Kim, M.D.1, 3 |
Department of Internal Medicine1
Department of Pathology2
Kidney Research Institute3 Hallym University College of Medicine, Chuncheon, Korea |
| 증례 : 신장침범을 동반한 Castleman병 1예 |
| 원지언1 정선주1 조재현1 김제열1 김은정1, 3 김형직1, 3 송영림3 남은숙2, 3 김성균1, 3 |
| 한림대학교 의과대학 내과학교실1, 병리학교실2, 신장연구소3 |
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| Abstract |
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Castleman's disease is a rare disorder of unknown etiology that results in the unregulated growth of lymphoid tissue. It can be classified as unicentric and multicentric based on clinical and radiological findings, and also as hyaline vascular and plasma cell type based on histopathology. Castleman's disease may present as an asymptomatic involvement of one lymph node group or as a multicentric disease with systemic features. However, renal involvement is very rare.
Here we report a 50-year old male patient with histopathologically proven multicentric plasma cell type of Castleman's disease who presented with weight loss, palpable cervical lymphadenopathy, azotemia and proteinuria. The finding of a percutaneous needle renal biopsy was compatible with plasma cell type of Castleman's disease. After treated with systemic corticosteroid, azotemia and proteinuria disappeared.
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| Key Words:
Castleman's disease, Plasma cells, Kidney |
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