A Case of Recurrent Extramammary Paget’s Disease after Kidney Transplantation

Korean Journal of Nephrology 2009;28(6):693-696.

Young Wook Roh, M.D.1, Kyu Sig Hwang, M.D.1, Myung Ho Jeong, M.D.1, Joon-Sung Park, M.D.1, Chang Hwa Lee, M.D.1, Gheun-Ho Kim, M.D.1, Seung Sam Paik, M.D.2, Jeong Tae Kim, M.D.3 and Chong Myung Kang, M.D.1

Departments of Internal Medicine¹
Pathology²
and Plastic Surgery³
Hanyang University College of Medicine, Seoul, Korea

증례 : 신이식 환자에서 발생한 재발성 유방외 파제트병 1예

노영욱1, 황규식1, 정명호1, 박준성1, 이창화1, 김근호1, 백승삼2, 김정태3, 강종명1

한양대학교 의과대학 내과학교실1, 병리학교실2, 성형외과학교실3

Abstract

The incidence of malignant disease increases in kidney transplant recipients taking immunosuppressive therapy. Extramammary Paget's disease, a very rare dermatologic malignancy, is characterized by frequent recurrences and coexistence with other malignancies. Although skin cancer is the most common malignancy occurring after kidney transplantation, extramammary Paget's disease has not been reported in Korea. In this paper, we report a case of recurrent extramammary Paget's disease after renal transplantation. A 66-year old man, who underwent renal transplantation from a living unrelated donor 15 years ago, was diagnosed to have extramammary Paget's disease 7 years ago. At this admission he was troubled with a pruritic skin lesion in his suprapubic area which previously occurred twice. The recurring Paget’s disease was treated with radical resection and coverage. No further recurrences have been developed during the following 12 months until now.

Key Words: Paget's disease, extramammary, Kidney transplantation, Skin neoplasms