A Case of Tumoral Calcinosis in a Hemodialysis Patient with Secondary Hyperparathyroidism

Korean Journal of Nephrology 2010;29(3):398-402.

Woo Sun Rou, M.D.1, Hyo Keun Lee, M.D.1, Kum Hyun Han, M.D., Ph.D.1, Deok Weon Kim, M.D., Ph.D.2, Yong Hoon Kim, M.D., Ph.D.3, Mee Joo, M.D., Ph.D.4 and Sang Youb Han, M.D., Ph.D.1

Departments of Internal Medicine¹
Orthopedics²
Radiology³
Pathology⁴
Inje University College of Medicine, Goyang, Korea

증례 : 부갑상샘기능항진증이 있는 혈액투석 환자에게서 발생한 종양성 석회증 1예

류우선1 , 이효근1 , 한금현1 , 김덕원2 , 김용훈3 , 주 미4 , 한상엽1

인제대학교 의과대학 내과학교실1 , 정형외과학교실2 , 영상의학교실3 , 병리학교실4

Abstract

Tumoral calcinosis is a periarticular calcific lesion and rare complication in patients with maintenance hemodialysis. The pathogenesis of tumoral calcinosis is poorly understood but may be due to elevated serum phosphorus, a high calcium phosphorus (Ca×P) product or secondary hyperparathyroidism in hemodialysis patients. A 30-year-old man presented with pain and palpable mass of left shoulder. He had been on maintenance hemodialysis with high flux dialyzer for 10 years. Laboratory finding showed hyperphosphatemia and elevated intact PTH concentration. A shoulder X-ray and CT scan demonstrated a massive calcification. Following partial resection, pain was relieved. Here we report a case of tumoral calcinosis of sh+oulder in a hemodialysis patient with untreated hyperphosphatemia and secondary hyperparathyroidism.

Key Words: Calcinosis, Hemodialysis, Hyperphosphatemia, Hyperparathyroidism