| Delayed Recovery of Sedation by Continuous Midazolam Infusion in an ESRD Patient on Peritoneal Dialysis: A Case Report |
| Hye-Jin Choi, M.D., So-Young Kim, M.D., Hae-Jin Choi, M.D., Hyun-Sik Park, M.D., Seon-Ung Yun, M.D., Byeong-Joo Bae, M.D., Jung-Hwan Park, M.D. Jong-Ho Lee, M.D. and Young-Il Jo, M.D. |
| Division of Nephrology, Department of Internal Medicine, Konkuk University School of Medicine, Seoul, Korea |
| 증례 : 복막투석 중인 말기신부전 환자에서 지속적인 midazolam 정주에 의한 진정 상태의 지연 회복 |
| 최혜진, 김소영, 최혜진, 박현식, 윤선웅, 배병주, 박정환, 이종호, 조영일 |
| 건국대학교 의학전문대학원 내과학교실 |
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| Abstract |
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Midazolam, a benzodiazepine derivatives, is widely used in intensive care unit for sedation of patients who require mechanical ventilation. Although midazolam has a short acting time, it might cause a prolonged sedation, especially in patients with renal failure. We report the case of a 76-year-old man who received peritoneal dialysis and showed prolonged sedation after stopping continuous infusion of midazolam. The patient who has received maintenance hemodialysis for five months admitted in intensive care unit to manage pneumonia and severe congestive heart failure. In ICU, hemodialysis was transferred to peritoneal dialysis due to severe cardiac dysfunction. He was treated with mechanical ventilation under sedation with midazolam. However, even though stopping midazolam, deep sedation by midazolam was not restored. The patient completely recovered from sedation after 280 hours. |
| Key Words:
Midazolam, Deep sedation, Kidney failure, chronic, Peritoneal dialysis |
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