A Case of a Kidney Transplant Recipient with Pulmonary Cytomegalovirus and Nocardia Coinfection with Cytomegalovirus Nephropathy |
Inwhee Park1, Hyunee Yim2, Lim Seung-Kwan3, Sukyong Yu1, Jinhee Cho1, Heungsoo Kim1, and Gyu-Tae Shin1 |
Departments of Nephrology1 Pathology2 Pulmonary and critical care Medicine3 Ajou University School of Medicine, Suwon, Korea |
증례 : A Case of a Kidney Transplant Recipient with Pulmonary Cytomegalovirus and Nocardia Coinfection with Cytomegalovirus Nephropathy |
Inwhee Park1, Hyunee Yim2, Lim Seung-Kwan3, Sukyong Yu1, Jinhee Cho1, Heungsoo Kim1, and Gyu-Tae Shin1 |
Departments of Nephrology1, Pathology2, Pulmonary and critical care Medicine3, Ajou University School of Medicine, Suwon, Korea |
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Abstract |
This is the first reported case of a kidney Transplant patient in Korea who developed cytomegalovirus and Nocardia pulmonary coinfection simultaneously with cytomegalovirus nephropathy. The patient had a history of end stage renal disease on peritoneal dialysis, diabetes mellitus and pulmonary tuberculosis. He underwent unrelated living kidney transplantation in China. About 5 months after transplantation, he developed high fever and rising serum creatinine for which he was admitted to hospital bronchiolitis obliterans with organizing pneumonia. Culture of lung biopsy tissue grew Nocardia farcinica. In addition, he was found to have CMV infection in kidney tissue with positive CMV antigen assay of blood. This case emphasizes that CMV infection, through its effect on systemic immunity, may increase the risk of other opportunistic infection. |
Key Words:
Cytomegalovirus, Nocardia, Kidney transplantation |
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