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| 심상성 건선과 건선성 관절염에 동반된 IgA 신증 1예 (A Case of IgA Nephropathy Associated with Psoriasis Vulgaris and Psoriatic Arthritis) |
| 신호진, 배우형, 송상헌, 이우철, 이수봉, 박성민, 곽임수, 나하연 (Ho Jin Shin, Woo Heong Bae, Sang Hun Song, Woo Chul Lee, Soo Bong Lee, Sung Min Park, Ihm Soo Kwak and Ha Yeon Rha) |
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| Abstract |
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IgA nephropathy was found in a 21-year-old woman with psoriasis vulgaris. She was first diagnosed as psoriasis vulgaris at 12 years age and had exhibited microscopic hematuria and proteinuria since 20 years of age. The histological findings of the renal biopsy showed mesangial proliferative glomerulonephritis and sclerosis. Mensangial deposits of IgA were observed by immunofluorescence. Therefore, we diagnosed this case as IgA nephropathy. Immune abnormalities have been reported in both diseases. The pathogenesis of psoriasis vulgaris and IgA nephropathy may be related through an immune mechanism. The overlapping or coexistence of these conditions has rarely been reported. Thus we described with IgA nephropathy associated with psoriasis vulgaris, psoriatic arthritis, and review the literatures. |
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