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신이식 환자에서의 파종성 Nocardiosis1예 (A Case of Disseminated Nocardiosis in Kidney Transplant Recipient) |
정항재, 김병덕, 이은영, 조규향, 박준범, 배성화, 김영진, 도준영, 윤경우 (Hang Jae Jung, Bung Duk Kim, Eyn Young Lee, Kyu Hang Cho, Sung Wha Bae, Jun Bum Park, Young Gin Kim, Jun Young Do and Kyung Woo Yoon) |
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Abstract |
Nocardiosis is a rare infection seen most commonly in immunocompromized patients. Most patients have pulmonary involvement, but some develop disseminated infection. A 52-year-old man, treated with immunosuppressive drugs for 3 months after kidney transplantation, developed pulmonary nocardiosis and disseminated infection involving brain, skin, and both uvea. The diagnosis was made by open lung biopsy specimens showing characteristic weak acid fastness with modified Ziel-Neelsen stainig and histologic examination. Immunosuppressive therapy was continued and combination of surgical drainage of brain abscess and chemotherapy with Minocycline were successful. With the increasing number of allograft recipients and concomitant immunosuppression, the possibility of an increase in Nocardia opportunistic infections exists. |
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