Korean Journal of Nephrology 1997;16(4):747-752.

말기신부전 환자에서 혈액투석 전후의 좌심실기능 변화에 관한 연구

김양욱 , 김두일 , 김영훈

Abstract

The cardiac function of the patients with chronic renal failure, who have had routine hemodialysis for long period is influenced by many factors including hypertension, anemia, artherosclerosis, interdialytic fluid collection and acidosis. Also the fluid shifts that occur during dialysis can alter left ventricular loading conditions. Hemodialysis may also influence left ventricular contractility by virture of its ability to correct electrolyte imbalances, BUN, hematocrit and concentration of inotrophics. Ten patients with chronic renal failure, who have hemodialysis during more than 6 months were stu died for the effect of hemodialysis on left ventricular function through echocardiography. 1) Body weight and systolic blood pressure were decreased(P<0.05) and diastolic blood pressure mean arterial blood pressure and heart rate did not increased significantly. 2) Serum calcium increased and BUN and serum potassium decreased significantly(P<0.05). 3) The prolonged preejection period, decreased left ventricular ejection time, stroke volume, endsystolic wall stress and increased rate corrected velocity of circumferential fiber shortening, shortening fraction had statistical significance. In conclusion, hemodialysis can improve cardiac function as decreased preload and increased left ventricular contractility from the patients with chronic renal failure.