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| Mannitol투여후 발생한 급성 핍뇨성 신부전증 1예 |
| 김미영 , 박용근 , 박철휘 , 장윤식 , 방병기 |
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| Abstract |
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Mannitol is known as metabolically inert alcohol and osmotic agent. It is widely used to reduce in- tracranial and intraocular pressure, to convert oligu- ric to nonoliguric ARF, and used as a diuretic agent in an attempt to prevent acute renal failure(ARF) in surgery. And now, it has been published that pati- ents with underlying renal impairment are more susceptible to mannitol intoxication due to decreased excretion rate. We report herein a case of mannitol induced- acute renal failure and intoxication occurred in a 55-year old female patient with cerebral infarction. Her baseline serum creatinine and BUN were normal. Mannitol was prescribed to reduce intracranial pressure. Mannitol induced-ARF with increased osmolal gap and clinical signs of mannitol intoxi- cation were developed and treated successfully by early HD. |
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