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| 원발성 사구체신염 환자의 혈청 IgE 측정의 의의 |
| 은연기 , 안재형 , 이태원 , 임천규 , 김명재 |
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| Abstract |
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Serum IgE was measured by RIST test in 120 cases of primary glomerular diseases and 28 normal heathy persons at the Kyung Hee Medical Center from May 1988 to June 1989. The results were as follows. 1) Serum IgE level was significantly elevated in MCD (608±395 U/ml, p<0.001), MGN (442±292 V/ml, p<0. 01) and FSGS (357±307 U/ml, p<0.05) as compared with normal normals (145±98 U/ml). 2) In MCD, the steroid-dependent/resistant group (846±410 U/ml) had significatly higher serum IgE level than the steroid-respontive group (412±350 U/ml) (p<0. 05). 3) In MGN, there was no significant difference in serum IgE level between the patients with nephrotic syndrome (468±89 u/ml) and those without nephrotic syndrome (486± 43 u/ml). 4) In FS(S. the patients with nephrotic syndrome (480± 213 u/ml) had significantly higher serum IgE level than those without nephrotic syndrome (193±89 u/ml) (p < 0.05). 5) In IgA nephropathy, serum IgE level was signifi- cantly elevated in the patients with nephrotic syndrome (569±342 u/ml, p<0.05) as compared with normal con- trols, but not in those withrout nephrotic syndn>me (112±124 u/ml). The patients I with nephrotic syndrome had significant 3y higher serum IgE level than those without nephrotic syndrome (p<0.01). |
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