Korean Journal of Nephrology 1989;8(2):355-360.
만성 신부전증 환자에서 발생한 악성종양 3예
오종흥 , 윤종일 , 박동준 , 구완서 , 김철민 , 심규식 , 강문원 , 허미경
Abstract
The malignancy in renal transplantation was reported in 1968 and the relationship between chronic renal fail- ure and malignancy was reported in 1975 by Matas. After then, many literatures were reported the incidence of malignancy was increased in chronic renal faiIure. The increased cancer risk in chronic renal failure might be related to loss of immunosurveillance, activa- tion of oncogenic virus and chronic immunostimulation by graft. Recently we experienced 3 patients with malignancy in chronic renal failure (squamous cell car- cinoma of lung, small cell carcinoma of lung, adenocar- cinoma of stomach). For the evaluation of the cancer risk in chronic renal failure, more comprehensive study will be necessary.
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