Korean Journal of Nephrology 1984;3(2):143-151.

소아신질환에서의 B형 간염 표지에 관한 연구

이영철 , 최정혜 , 이재승 , 김병길

Abstract

We studied Hepatits B virus markers in sera & venal tissues in 830 patients with renal diseases, who were admitted to our hospital from Jan. '79 to Mar.' 84, and in sera of their family members. Among 830 cases of renal disease, 67 cases(8. I %) and among 407 cases of biopsy proven renal diseases, 52 cases(12. 8%) were positive for HBsAg, while HBs antigenemia in control group was 4, 8% (8 of 167). The incidence of positive serum HBsAg in renal diseases was not statistically higher than control group.(p>0.05) The 57 cases(6.9%) in renal disease group and 14 cases(8. 4%) in control group were positive for anti-HBs. The incidence of HBs antigenemia was conside- rably higher in Mesangioproliferative glomerulone- phritis and membranous glomerulonephritis than control group, but the incidence of positive anti- HBs in thoae two groups was not. Glomerular depositions of HBsAg were identified in 5 of 8 cases of membranous glomerulonephritis with HBs antigenemia by immunofluorescent micro- scopy. The incidences of HBsAg & anti-HBs in family members of renal disease patients with HBsAg were 32. 0% respectively.