| Mandibular Enlargement, Metastatic Pulmonary Calcification and Gastric Mucosal Calcinosis in a Patient with Chronic Kidney Disease-mineral Bone Disorder |
| Jeong-Yup Kim, M.D.1, Jeong-Seon Kim, M.D.1, Joon-Kwang Wang, M.D.1, Sang-Won Park, M.D.1, Young-Mo Lee, M.D.1, Ji-Eun Lee, M.D.2, Eun-Sil Jeon, M.D.1, Heui-Jung Pyo, M.D.1, Young Joo Kwon, M.D.1 and Jae-Bok Lee, M.D.3 |
Division of Nephrology1
Department of Internal Medicine, College of Medicine, Korea University, Division of Nephrology2
Department of Internal Medicine, Wonkwang University, Division of Breast and Endocrine Surgery3
Department of surgery, Korea University |
| 증례 : 이차성부갑상샘항진증을 가진 만성신부전 환자에서 하악골 종대 및 폐, 위점막 석회 침착 1예 |
| 김정엽1, 김정선1, 왕준광1, 박상원1, 이영모1, 이지은2, 전은실1, 표희정1, 권영주1, 이재복3 |
| 고려대학교 내과학교실 신장내과1 , 원광대학교 내과학교실 신장내과2, 고려대학교 외과학교실 유방내분비외과3 |
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| Abstract |
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Secondary hyperparathyroidism is one of the most common complications of patients with chronic kidney disease (CKD). Mandibular enlargement, metastatic pulmonary calcification, and gastric mucosal calcinosis are rare complications in these patients. The defect of calcium and phosphorus metabolism may precipitate pathologic calcification at diverse organs and soft tissue, and change bone architecture.
In case of involving periarticular area, patients usually present with localized swelling, pain, and reduced mobility in affected sites. However, in case of organ involvement, except in an advanced stage of disease, there are no specific symptoms. Among these patients, treatment strategies include tight control of calcium and phosphate levels, parathyroidectomy for hyperparathyroidism, renal transplantation, and local excision of calcific lesions. We report a case of mandibular enlargement, metastatic pulmonary calcification, and gastric mucosal calcinosis due to CKD with improvement 3 months after medical and surgical treatment. |
| Key Words:
Secondary hyperparathyroidism, Pathologic calcification |
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