Kaposi’s Sarcoma in a Patient on Hemodialysis

Korean Journal of Nephrology 2010;29(4):525-528.

Seok hu Jeong, M.D.1, Kyong yong Oh, M.D.1, Dong Su Shin, M.D.1, Shung Han Choi, M.D.1, Eul Sik Jung, M.D.1, Jin Sun Park, M.D.1, Sun Young Na, M.D.1, Ji Yoon Sung, M.D.1, Ji Yong Jung, M.D.1, Sejoong Kim, M.D.1, Hyun Hee Lee, M.D.1, Woo Kyung Chung, M.D.

Departments of Internal Medicine1 and Pathology²
Gachon University Gil Hospital, Gachon University of Medicine and Science, Incheon, Korea

증례 : 혈액투석 환자에서 발생한 카포시육종 1예

정석후1 , 오경용1 , 신동수1 , 최성한1 , 정을식1 , 박진선1 , 나선영1, 성지윤1 , 정지용1 , 김세중1 , 이현희1 , 정우경1 , 박상희2 , 장제현1

가천의과학대학교 길병원 내과1 , 병리과2

Abstract

Kaposi’s sarcoma (KS) is an unusual multifocal neoplasm of vascular endothelial cell origin. The trunk, arms, head, and neck are the most common sites. It is common in men and has four distinct variants: classic, Africa-endemic, immunosuppressive drug-associated, and acquired immunodeficiency syndromeassociated KS. KS appears to develop immunosuppressed patients, but is uncommon in patients on dialysis. A 79-year-old man on hemodialysis for 2 months presented with pruritus over the entire body and multiple, discrete, variable-sized, dark blue papulonodules (papuloplaques, maculopapules) on the left arm and shoulder. A biopsy specimen form the left arm showed spindle cells with slit-like spaces and extravasated red blood cells. The specimen was positive for CD 34 antigen, and human herpesvirus 8 was detected. We report a case of KS that occurred in a 79-year-old patient on hemodialysis.

Key Words: Kaposi sarcoma, Hemodialysis, HHV-8