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Korean Journal of Nephrology 2008;27(2):238-242.

Dong Hwan Ryu, M.D.1, Seok Min Kim, M.D.1, Jong Won Park, M.D.1, Jun Young Do, M.D.1, Kyung Woo Yoon, M.D., Hee Soon Cho, M.D.2 and Yong Jin Kim, M.D.3

Department of Internal Medicine¹
Laboratory Medicine2 and Pathology Yeungnam University Hospital, Daegu, Korea

증례 : Multiple Myeloma Presented as Tubulointerstitial Nephritis

포천중문의과대학 내과학교실

Abstract

Oral sodium phosphate is commonly used to evacuate the colon and rectum before colonoscopy or colorectal surgery. However, this substance is known to cause electrolyte abnormalities including hyponatremia. The hyponatremic patient usually presents with headache, nausea, vomiting and confusion, but can also present with non-cardiogenic pulmonary edema, seizure and rhabdomyolysis. However, non-cardiogenic pulmonary edema, seizure and rhabdomyolysis caused by hyponatremia associated with bowel preparation have only rarely been reported. We report a case of severe complications including non-cardiogenic pulmonary edema, seizure and rhabdomyolysis associated with hyponatremia following ingestion of sodium phosphate for colonoscopy in a 41-year-old healthy male.

Key Words: Hyponatremia, Pulmonary edema, Seizure, Rhabdomyolysis