| A Case of Adult-onset Henoch-Schönlein Purpura (HSP) Combined with Post-infectious Glomerulonephritis (PIGN) |
| Kyoung Min Moon, M.D.1, Joo Hyung Kang, M.D.2, Dong Gyu Kim, M.D.1, Woong Chul Lee, M.D.1, Yu Ri Moon, M.D.1 , Jong Eun Joo, M.D.3, Yong Il Kim, M.D.3, Seoung-Oh Yang, M.D.4 and Young Sook Lee, M.D.1 |
Department of Internal Medicine1
Department of Pediatrics2
Pathology3 and Radiology4 Eulji University Hospital, Eulji University School of Medicine, Daejeon, Korea |
| 증례 : 급성 감염후 사구체 신염이 동반된 성인 Henoch-Schönlein 자반증 1례 |
| 문경민1, 강주형2, 김동규1, 이웅철1, 문유리1, 주종은3, 김용일3, 양승오4, 이영숙1 |
| 을지대학교 의과대학 내과학교실 신장내과1, 소아과학교실2, 해부병리학교실3, 영상의학교실4 |
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| Abstract |
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Henoch-Schönlein purpura (HSP) is a small-vessel vasculitis that are predominantly observed in children, affecting their skin, joints, gut and kidneys. The renal prognosis of HS nephritis is known to be worse in adults than in children. It is defined by tissue deposition of IgA. In most HSP patients, serum complement levels are usually normal. However, some authors reported abnormalities of serum complement levels in children-onset HSP. The authors report here a rare adult-onset case of HSP combined with post-infectious glomerulonephritis, especially hypocomplementemia and subepithelial 'hump'- like electron dense deposits. |
| Key Words:
Purpura, Schoenlein-Henoch, Glomerulonephritis, Complement system proteins |
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