| A Case of Rapidly Progressive Glomerulonephritis in a Hepatitis B Virus Carrier Successfully Treated with High dose Immunosuppressive Therapy and Prophylactic Lamivudine |
| Jung Eun Lee, M.D.1, 3, Jung Myung Lee, M.D.1, Jung Tak Park, M.D.1, 3, Kyu Hun Choi, M.D.1, 3, Ho Yung Lee, M.D.1, 3, Dae-Suk Han, M.D.1, 3, Hyeun Joo Jeong, M.D.2, 3 and Beom Seok Kim, M.D.1, 3 |
Department of Internal Medicine1 and Pathology2
Institute of Kidney Disease3
Yonsei University College of Medicine, Seoul, Korea |
| 증례 : A Case of Rapidly Progressive Glomerulonephritis in a Hepatitis B Virus Carrier Successfully Treated with High dose Immunosuppressive Therapy and Prophylactic Lamivudine |
| Jung Eun Lee, M.D.1, 3, Jung Myung Lee, M.D.1, Jung Tak Park, M.D.1, 3, Kyu Hun Choi, M.D.1, 3, Ho Yung Lee, M.D.1, 3, Dae-Suk Han, M.D.1, 3, Hyeun Joo Jeong, M.D.2, 3 and Beom Seok Kim, M.D.1, 3 |
| Department of Internal Medicine1 and Pathology2, Institute of Kidney Disease3, Yonsei University College of Medicine, Seoul, Korea |
|
|
| Abstract |
|
A 35-year-old man, previously hepatitis B surface antigen (HBsAg) carrier, presented with gross hematuria and heavy proteinuria that he had been suffering from for 1 month. Serum creatinine was 4.4 mg/dL. Renal biopsy showed pauci-immune crescentic glomerulonephritis. He received plasmapheresis and was treated with high-dose steroids and cyclophosphamide. Lamivudine was started for the prevention of hepatitis B virus (HBV) activation. Serum creatinine and proteinuria were ameliorated one week after the treatment. There was no sign of HBV activation after six months of treatment. We report a case of rapidly progressive glomerulonephritis in a HBV carrier successfully treated with high dose immunosuppressive therapy and prophylactic lamivudine. |
| Key Words:
Lamivudine, Hepatitis B virus, Rapidly progressive glomerulonephritis |
|
PDF Links
Download Citation
