| A Case of Acute Lithium Intoxication Treated with Continuous Venovenous Hemodiafiltration |
| Soon-Young Ko, M.D.1, Tae-Ho Seo, M.D.1, Seung-Min Lee, M.D.1, Jung-Hwan Park, M.D.1 Young-Il Jo, M.D.1, Seung-Ho Yoo, M.D.2 and Jong-Ho Lee, M.D.1 |
Department of Internal Medicine1
Psychiatry2 , Konkuk University Hospital Konkuk University School of Medicine, Seoul, Korea |
| 지속성 정정맥 혈액투석여과로 치료한 급성 리튬 중독 1예 |
| 고순영1 서태호1 이승민1 박정환1 조영일1 유승호2 이종호1 |
| 건국대학교 의학전문대학원 건국대학교병원 내과학교실1, 신경정신과교실2 |
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| Abstract |
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Lithium is commonly used for the treatment of bipolar affective disorders. Lithium therapy has a narrow therapeutic window, which can lead to various neurologic, cardiovascular, and renal side effects. Dialysis is recommended for the treatment of severe lithium toxicity, but conventional hemodialysis can cause post-dialysis rebound of serum lithium level. We report a case of lithium intoxication in which continuous venovenous hemodiafiltration (CVVHDF) was successfully used in reducing toxicity. CVVHDF provides excellent lithium clearance, and prevents post-therapy lithium rebound by allowing a progressive removal of intracellular lithium. It could become a modality of choice for lithium intoxication. |
| Key Words:
Lithium, Dialysis, Hemodiafiltration |
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