Korean Journal of Nephrology 2007;26(4):465-468.
A Case of Cystadenocarcinoma of the Pancreas in a Patient with Autosomal Dominant Polycystic Kidney Disease
Soo Youn Lee, M.D., Young Jun Yang, M.D., Dong Seok Jang, M.D., Young Mo Lee, M.D., Ki-Ryang Na, M.D., Byung Seok Lee, M.D., Kang Wook Lee, M.D. and Young Tai Shin, M.D.
Division of Nephrology, Department of Internal Medicine, College of Medicine; Chungnam National University, Daejeon, Korea
상염색체우성 다낭신에 동반된 췌장의 낭샘암종
이수윤
충남대학교 의과대학 내과학교실
Abstract
Polycystic kidney disease is an autosomal dominant disease that may be associated with liver and pancretic cysts. Mitral valve prolapse and intracranial berry aneurysms are also well-known manifestations of autosomal dominant polycystic kidney disease (ADPKD). Cystadenocarcinoma of the pancreas is uncommon and accounts for only 1% of primary pancreatic malignancies. Few cases were reported to have an association of ADPKD and pancreatic malignancies. We report a 63-year-old man with ADPKD who was admitted to our hospital with anorexia and severe weight loss. After abdominal CT and histologic examination, he was diagnosed as pancreatic cystadenocarcinoma with lung, spleen, and liver metastasis. To prolong the life of the patient, we tried gemcitabine and cisplatin combination chemotherapy. But the patient died 2 months after diagnosis due to the disease progression.
Key Words: Polycystic kidney diseases, Pancreatic neoplasms, Cystadenocarcinoma


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