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| 만성 B형 간염환자에서 Interferon - alpha 치료 중 발생한 횡문근융해증을 동반한 급성 신부전 1예 |
| 이상수 , 박동준 , 천일석 , 임정욱 , 정운태 , 이종덕 , 조중현 , 장세호 , 정순일 |
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| Abstract |
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Interferon has been tried as a drug of choice in patients with chronic active hepatitis by hepatitis B virus infection sinee Greenberg has reported the effectiveness of interferon in 1976. The effects of interferon therapy have been reported variably and various complications such as fever, myalgia, arth- ralgia, flu-like symptoms, temporary leukopenia and thromhocytopenia, alopecia, cardiovascular symptoms and autoimmune diseases have been reported. But rhabdomyolysis has been rarely reported in the interferon therapy of chronic hepatitis B. There were some cases of rhaMomyolysis with acute renal failure in the interferon therapy which was designed for chemotherapy of malignant mela- noma and for chronic active hepatitis C virus infection. We reported a case of rhabdomyolysis with acute renal failure developed during the interferon therapy in a patient with chronic active hepatitis B. |
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