Korean Journal of Nephrology 1997;16(3):603-606.
충수 주위 농양과 연관된 용혈성 요 독 증후군 1예
김병수 , 김석영 , 문성배 , 윤성노 , 이영숙 , 김형욱 , 김종민 , 진동찬 , 방병기
Abstract
The hemolytic uremic syndrome (HUS) is clini- cally characterized by microangiopathic hemolytic anemia, thrornbocytopenia and acute renal failure. The unique cause has not been determined but sorne bacteria such as E. coli was regarded as the causative agent of HUS in infant. A 30-year-old male patient was admitted due to acute aMomen. In operating field, the periappendiceal abscess was found, so the appendectomy with the drainage of abscess was performed. Initial hemoglobin level was 16.2g/dL but abruptly developed anemia (12.6g/dL) and thrombocytopenia (27000/mm) was detected at hospital day 3. The urinary outflow was totally absent, the serum crea- tinine was 12.8mg/dL and the LDH was 3,650IU/L. The peripheral blood smear showed strong evi- dence of microangiopathic hemolysis. We performed total plasma exchange and hemodialysis under the diagnosis of HUS. The patient's renal function was markedly improved and the last creatinine was 1.9mg/dl. To our knowledge, this is the first report of HUS associated with periappendiceal abscess in Korea. We present a case and the review of literature.
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