|
| 원발성 신질환 환자에서 임신이 신기능가 태아에 미치는 영향 |
| 신영신 , 이승헌 , 양철우 , 김석영 , 최의진 , 장윤식 , 방병기 |
|
|
| Abstract |
|
The influences of pregnancy on the renal function and fetal outcome were retrospectively studied in the patients with primary glomerular diease. The clinical courses of 38 pregnancies in 32 women from 1980 through 1994 were analyzed with pre- and post- pregnant serum creatinine levels, 24hr proteinuria, and blood pressure. The results were as follows' 1) The fetal outcomes of total pregnancies were 20 normal deliveries(52.6%), 8 prematurities(21.1%), and 10 fetal losses(8 spontaneous abortions, 2 still births)(26.3%). 2) Seven pregnancies with prepregnant serum creatinine level of 1.4mg/dl or more showed more rapid deterioration of renal function and higher fetal loss rate than twenty eight cases with prepregnant serum creatinine less than 1.4mg/dl (p=0.001). 3) Twelve pregnancies with prepregnant blood pressure of 140/90 mmHg or more had more adverse effects on their renal function and fetal outcomes than twenty six cases with prepregnant normal blood pressure (p=0.0005). 4) Six pregnancies with prepregnant nephotic range proteinuria did not have more adverse effects on the their renal function and fetal outcomes than twenty four cases with prepregnant nonnephrotic proteinuria. 5) In twenty pregnancies with Ig A nephropathy, normal and abnormal deliveries were 16(80%) and 4 cases(20%), respectively. Authors concluded that pregnant women who had moderate renal insufficiency and hypertension were frequently accompanied by decline in the renal function and poor fetal outcome. |
|
PDF Links
Download Citation
