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| 지속적인 투석환자에서 혈청전립선 특이 항원 농도의 변화 |
| 김재헌 , 박상석 , 이제경 , 박성광 ,강성귀 |
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| Abstract |
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Prostate specific antigen(PSA) is most clinically useful tumor marker for the diagnosis and mana- gement of the prostate cancer. Little is known about mechanism of removal from serum PSA, Auther undertook a prospective study to evaluate the effect of hemodialysis(HD) and chronic ambulatory peri- toneal dialysis(CAPD) on PSA in 31 male patients with end-stage renal disease as a clinical model for assessing the role of kidney in PSA clearance The mean age of HD, CAPD, chronic renal failure before initiating dialysis (BD), and control group were 39.8, 48.9, and 43.5 years, respectively. Serurn PSA values determined by radioimmunoassay (ELSA-PSA kit ) and no rectal examination for 1 week prior to blood sampling. Serum PSA values of patients were HD 1.0± 0.2ng/ml, CAPD 0.8± 0.2ng/ml, BD 1.3± 0.2ng/ml, and normal group 1.2±0.2ng/ml. There was no statistically significant differences on each groups. These suggested that PSA is not eliminated by hemodialysis, CAPD and recommand using PSA determinations in patients with CRF and patients on dialysis in the same manner they are used in normal person. |
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