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| 용혈성 요독증후군 2예 |
| 김창수 , 진동규 , 석준 , 김동진 , 박훈기 , 정태시 , 차대룡 , 조원용 , 김형규 |
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| Abstract |
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Hemolytic uremic syndrome is a clinically character- ized by microangiopathic hemolytic anemia, throm- bocytopenia and acute renal failure. The precise etiology of hemolytic uremic syndrome is unknown, but has been generally accepted that hemolytic uremic syndrome represents a variable num- ber of different causes, including infections, genetic, enviornmental, phamacological factors, pregnancy and puerperium. The pathogenesis of the hemolytic uremic syndrome is uncertain, until recently, but probably involves glomerular endothelial cell injury, and widespread intravascular platelet aggregation has been considered a crucial event in the pathogenetic sequence. Several combinations of treatments have been used over the years, still no form of therapy has been deter- mined to be effective. In adults with severe disease, treatment with plasmapheresis, in addition to hemodialysis, steroids, and antiplatelet agents, is prob- ably indicated. We experienced two cases of hemolytic uremic syn- drome and report with a brief review of literature. |
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