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| 증례 : 저나트륨증을 동반한 Wernicke`s encephalopathy 1예 (A Case of Wernicke`s Encephalopathy with Hyponatremia) |
| 안선호(Seon Ho Ahn),이재홍(Jae Hong Lee),이명수(Myeung Su Lee),송주홍(Ju Hung Song),이성근(Seong Keun Lee),박병현(Byoung Hyun Park),구기선(Ki Seon Gu) |
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| Abstract |
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Thiamine deficiency is known to lead to certain neurologic sequales including Wernicke-Korsakoff syndrome. Wernicke's encephalapathy is charac-terized by ataxia, ophthalmoplegia, nystagmus, and mental change. Although classically associated with chronic alcoholism, a number of other predisposing conditions exist such as hyperemesis gravidarum, thyrotoxicosis, starvation, anorexia nervosa, prolonged total parenteral nutrition, gastric plication and renal dialysis. We have experienced a case of Wernicke's encephalopathy associated with prolonged starvation which was misdiagnosed by hyponatremic ence-phalopathy at first, and which seemed to be developed by thiamine-free dextrose infusion in 39-year-old male patient. We report the case with review of the literature and emphasize the need for thiamine supplementation with slow correction of hyponatremia before the infusion of dextrose solution in the prolonged starved hyponatremic patient. |
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