Korean Journal of Nephrology 2000;19(4):740-744.

루푸스 환자에서 급성 신우신염에 의해 합병된 급성 신부전과 허혈성 장질환 (Acute Renal Failure and Ischemic Bowel Disease Complicated by Acute Pyelonephritis in a Patient with Systemic Lupus Erythematosus)

최윤석(Yoon Suk Choi),김영옥(Young Ok Kim),조재형(Jae Hyung Jo),김정선(Jung Sun Kim),현영근(Young Geun Hyun),서정필(Jung Pil Seo),민준기(Joon Gee Min),윤선애(Sun Ae Yoon),방병기(Byung Gee Bang)

Abstract

Acute infection increases disease activity in patients with systemic lupus erythematosus(SLE) and causes life threatening complication such as acute renal failure or ischemic bowel disease. We here report a case of acute renal failure and ischemic bowel disease complicated by acute pyelonephritis in a patient with SLE. A 19-year-old woman was admitted for high fever and right flank pain. Urine examination revealed acute pyelonephritis. Thrombocytopenia, proteinuria, positive antinuclear antibody and anti-dsDNA, false positive VDRL confirmed SLE. The pyelonephritis improved with antibiotic treatment, but oliguria and abdominal pain and ascites newly developed. Kidney biopsy and abdominal computed tomography revealed lupus nephritis type IV and ischemic bowel disease, respectively. After methylpre-dnisolone and cyclophosphamide treatment, the patient improved.