Korean Journal of Nephrology 2000;19(6):1178-1182.
건선에 동반된 막성신병증 2예 (Two Cases of Membranous Glomerulopathy Associated with Psoriasis Vulgaris)
김수진(Soo Jin Kim),강정훈(Jung Hoon Kang),이대환(Dae Hwan Lee),김태효(Tae Hyo Kim),하혜정(Hye Jung Ha),정태식(Tae Sik Jung),김현정(Hyun Jung Kim),함종렬(Jong Ryul Ham),전은실(Eun Sil Jeon),장세호(Se Ho Jang),정순일(Soon Il Jung)
Abstract
Membranous glumerulonephrophy was found in two men who were diagnosed as psoriasis vulgaris. In the first patient, membranous glumerulonephropathy was developed during treatment of psoriasis and deterioration of proteinuria was appeared with aggravation of skin lesion although treated with cyclophosphamide. In the second patient, psoriasis developed during treatment of membranous glomerulonephropathy and we observed the improvement of nephrotic syndrome and psoriasis with prednisolone treatment. The simultaneous deterioratian and improvement of proteinuria and skin lesion of psoriasis suggests that underlying common immune abnormalities may be involved in the pathogenesis of both psoriasis and membranous glomerulopathy.
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