|
| 혈액 투석기의 재사용시 투석막에 따른 혈액 요소 질소와 β₂-Microglobulin 제거율의 변화 (Effects of Dialyzer Reuse on Clearances of Blood Urea Nitrogen and β₂ Microglobulin in the Three Different Membranes) |
| 고재민(Jae Min Ko),손진희(Jin Hee Son),정성오(Sung Oh Jung),이태훈(Tae Hoon Lee),조대경(Dae Gyung Jo),송성욱(Sung Wook Song),정예경(Ye Gyung Jung),전용덕(Yong Duk Jeon) |
|
|
| Abstract |
Background
We performed the study on the changes of β₂-microglobulin(β₂M) clearance and urea reduction ratio after reuse of dialyzers with three different membranes. Methods: 9 patients who had received regular hemodialysis rnore than five years were enrolled. Three kinds of dialyzer membrane were used; i.e. Two of them were high-flux and the other was low-flux. Dialyzer reprocessing was performed by an automated machine using glutaraldehyde and bleach. Each dialyzer was reused 10 times. Solute clearance was determined for each dialyzer after the 1st, 5th, 8th and 10th reuse. Results: Urea clearance was well maintained after reuse with both high-flux and low-flux membrane but β₂M clearance was significantly greater with high-flux dialyzers than low-flux dialyzer. Effects of each dialyzer reuse on β₂M clearance showed no significant decrease until the 10th reuse and no significant difference in β₂M clearance between the two high-flux dialyzers(polyamide vs PEPA membrane, p=0.197). Conclusion: Reuse of dialyzers was cost-effective. After reuse of dialyzer, clearance of solute ws maintained in both small & large solutes until the 1O th reuse. Further study is needed regarding the maintenance of solute clearance with increased number of reuses. |
|
PDF Links
Download Citation
