Korean Journal of Nephrology 1999;18(1):168-174.

Tc-99m DTPA 신장스캔을 이용한 이식신의 사구체 여과율 측정의 임상적 유용성의 평가 (Clinical Usefulness of GFR Measurement Using Tc-99m DTPA Renal Scan in Kidney Transplantation Patients)

감복규, 신용훈, 박용기, 윤대현, 장익득, 김미선, 김중경, 윤명순, 이시래 (Bok Gyu Gam, Yong Hoon Shin, Yong Ki Park, Dae Hyun Yun, Ik Deuk Jang, Mi Sun Kim, Joong Kyung Kim, Meung Soon Yun and Shi Rae Lee)

Abstract

In clinical practice, Tc-99m DTPA renal scan has been using for screening for the presence of renal dysfunction to determine the need for early treatment in kidney transplantation patients. We measured glomerular filtration rate(GFR) using Gates method during the routine Tc-99m DTPA renal scan, predicted creatinine clearance estimated by Cockcroft and Gault formula and 24-hour creatinine clearance and compared each other in 88 kidney transplantation patients simultaneously. The range of renal uptake(%) of Tc-99m DTPA was from 1.8% to 10.4% and the correlation between 24-hour creatinine clearance and renal uptake showed Y=7.176X8.975Y=creatinine clearance(ml/min), X=renal uptake(%) and the correlation coefficient was 0.771. The correlation coefficient between GFR (ml/min) using Tc-99m DTPA renal scan and predicted creatinine clearance was 0.765. The correlation coefficient between predicted creatinine clearance and 24-hour creatinine clearance was 0.850. We concluded that the measurement of GFR using Tc-99m DTPA renal scan was clinically useful in kidney transplantation patients with the advantage of simplicity, low expense, opportunity for renal imaging.