Korean Journal of Nephrology 1999;18(4):625-629.
음주후 발생한 근색소뇨증 및 급성 간질성 신염 1예 (A Case of Acute Interstitial Nephritis and Myoglobinuria after Alcohol Drinking)
나병주, 정오영, 이후석, 조한선, 정현주 (Byoung Ju Na, Oh Young Chung, Hu Seok Lee, Han Sun Cho and Hyeon Joo Jeong)
Abstract
Rhabdomyolysis is defined as skeletal muscle injury with release of muscle cell constituents into the plasma and may lead to acute renal failure secondary to myoglobinuria. The causes of rhabdomyolysis is diverse:alcohol abuse, primary muscle disease, disturbance of muscle metabolism, sustained seizure, infection, drugs, tox ins, trauma, severe exercise, CO intoxication etc. Rhabdomyolysis may cause acute derangement in electrolyte balance and death. It should be diagnosed earlier and managed properly. We experienced a 49 year-old woman developed acute renal failure and myoglobinuria after alcohol drinking. A kidney biopsy revealed acute interstitial nephritis. In the presence of otherwise unexplained acute renal failure in alcoholic patients, rhabdomyolysis should be considered in the differential diagnosis.
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