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| 막성사구체신염과 IgA 신병증이 증복되어 나타난 건선 1예 |
| 이윤하 , 이규백 , 김윤구 , 오하영 , 김미경 , 장세호 |
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| Abstract |
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A 17-year-old man with psoriasis developed albu- minuria and microscopic hematuria. Renal biopsy revealed a glomerulonephritis with features of both membranous glomerulonephritis and IgA nephro- pathy. Histologically the glomeruli exhibited variable degree of mesangial expansion and hypercellularity, three of which showed segrnental hyalinosis and/or sclerosis. Direct immunofluorescence demonstrated granular IgG-bearing deposits along the peripheral glomerular capillaries and IgA deposits in the mesangium. His urinary abnormalities persisted after the remission of skin lesion induced by PUVA treatment. It suggests that although the psoriasis may induce the renal lesion, it is insufficient to treat only the skin lesion for clinical improvement of glomerulonephritis after the renal lesion is already established. |
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