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| 장기간 투석치료중인 만성 신부전 환자에서의후천성 신 낭성 변화 |
| 김종호 , 박혜영 , 신언수 , 이홍규 , 한인수 , 김종유 , 장환준 , 이종호 |
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| Abstract |
Background
Acquired cystic kidney disease in long- term hemodialysis patients was first described by'Dun- nill et al in 1977. The incidence of cystic changes are reported to be related to the time on dialysis and malignant neoplasm is reported to be associated with acquired cystic kidney disease. Methods: To investigate cystic changes in long-term dialysis patients, 20 patients who were on dialysis more than 5 years were examined by computed tomography and their c@linical characteristics were analyzed. Results . 1) There were 9 men and 11 women and mean age was 43.9 (men: 38.2, women:48.5). Mean duration of dialysis was 69.2 months. 2) Nine patients (6 men and 3 women) had more than 5 cysts (group A), eight patients (3 men and 5 women) had 1 to 4 cysts (group B), and three-all women-showed no cystic changes (group C). There were no differences in incidence and number of cysts between two sexes. 3) The largest diameter of cyst in each patient ranged from 0.5 cm to 2.5 cm. 4) Mean duration of dialysis was 67.9±8.3 months in group A, 67.3±4.4 months in group B, and 78.3±11.5 months in group C. (p > 0.05). 5) Mean size of kidney was 6.1±0.7 cm in group A, 5. 5±1.2 cm in group B and 4.8±0.7 cm in group C. Mean size of group A was significantly greater than that of group C. (p<0.05). 6) Mean predialysis blood urea nitrogen level (BUN) was 82.4±21.8mg/dl in group A, 107.1±23.6mg/dl in group B, and 111.7±24.5 mg/dl in group C. (p>0.05) 7) Clinical symptoms were not found in most patients Colclusions . Acquired renal cystic changes were noted in 85% of long-term dialysis patients. Kidney size was increased in patients with more than 5 cysts. |
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