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| 혈액투석 치료를 받는 만성신부전증 환자의 C형간염의 빈도 |
| 엄재화 , 김태진 , 정재성 , 이성미 , 공진민 , 옥종환 , 원대식 |
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| Abstract |
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To determine the prevalence of anti-HCV in ESRD patients under chronic maintenance hemodialysis, 75 hemodialysis patients in our units and 66 age and sex matched control persons were studied. The mean age of hemodialysis patients was 45 (22-71). The duration of dialysis was 29.5±28.0 (0-120) months. 9 of 75 dialysis patients showed positivity in anti-HCV test and 1 of 66 control persons showed positivity (p <0. 05). All dialysis patients and the control person with anti-HCV (+) had the history of transfusion. The num- ber of transfusion units was significantly higher in the anti-HCV (+) dialysis patients (mean 34.2±25.7; range 2 to 69 units) in comparison with the number in the anti- HCV ( ). (mean 17.9±20.9; range 0 to 72 units; p<0,05). The duration of dialysis was also significantly longer in the anti-HCV (+) dialysis patients (mean 52.4±34.1; range 9 to 120 months) than that of the anti-HCV ( ). (mean 26.4+25.8; range 1 to 96 months; p<0.05). Among 10(13.3%) chronic NANB hepatitis patients, 4 had anti-HCV (+). Among 9 with anti-HCV (+), 4 were chronic NANB hepatitis, 1 was mixed infection by both B and C viruses and 4 were asymptomatic carriers with normal ALT level. We conclude that HCV is prevalent in hemodialysis unit and that HCV infection is significantly related with the number of transfusion units and the duration of hemodialysis. |
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