Korean Journal of Nephrology 1985;4(1):89-93.

만성 신부전 환자에서의 알루미늄과 Dihydrotachysterol ( DHT ) 의 치료 효과

최학림 , 우정택 , 장영운 , 임천규 , 김명재

Abstract

In order to make comparison of the effectiveness between aluminum compounds and dihydrotachy- sterol in the chronic renal failure patients unde- rgoing dialysis, the serum calcium, phosphorus, alkaline phosphatase and PTH levels were measu- red before and after treatment. The duration of treatment was between 3 months and 27 months. The calcium concentration of dialysate was 3.5 mEq/L. The serum calcium and phosphorus levels were significantly improved in patients treated with aluminum compounds. But the changes of serum- 1kaline phosphatase and PTH levels were not sig- nificant. In patients treated with aluminum com- pounds and DHT, the serum calcium was improved significantly. And the changes of serum phospho- rus and alkaline phosphatase level were not sign- ificant. The PTH level shows decreasing tendency. Consuming the effectiveness of the treatment was more than 30 percent improvement after trea- tment, the effe ctivechange of serum calcium level was observed in 10 patients(59%) in GrouP I and 4 patients(43%) in Group I The effective change of the serum PTH level was observed in 7 patients (41%.) in Group II and 2 patients(33%) in Group With the above results, it may be stated.that the effectiveness between aluminum compounds and DHT in view of increasing serum calcium and decreasing serum PTH, was not different signifi- cantly. But it may be needed to follow up for more long periods and in many more patients.