| One Case of Chronic Renal Failure and Another Case of Membraneous Glomerulonephritis Complicated by Acute A Viral Hepatitis |
| In Geol Song, M.D.1, Min Gyu Kang, M.D.1, Woon Tae Na, M.D.1, Sung Tae Kim, M.D.1, Moon Il Park, M.D.2, Se Hei Yun, M.D.1 and Sung Ro Yun, M.D.1 |
Department of Internal Medicine1
Department of Pathology2
Konyang University College of Medicine, Daejeon Korea |
| 증례 : 급성 A형 간염 이환 후에 만성신장병이 합병된 1예와 막사구체신염이 합병된 1예 |
| 송인걸1 , 강민규1 , 나운태1 , 김성태1 , 박문일2 , 윤세희1 , 윤성로1 |
| 건양대학교 의과대학 내과학교실1 , 병리학교실2 |
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| Abstract |
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Acute A viral hepatitis is a mild, self-limiting disease of liver and acute renal failure (ARF) is a rare complication. We report two cases of chronic renal failure (CRF) in nonfulminant acute A viral hepatitis and ARF. A 40-year-old man was admitted with ARF and acute A viral hepatitis, and underwent temporary hemodialysis therapy. The renal biopsy showed acute tubular necrosis with tubulointerstitial nephritis. At 13 months after discharge serum creatinine was 1.33 mg/dL and protein-creatinine ratio of spot urine was 0.47 (mg/mg Cr). The second case was a 28-year-old man and was managed conservatively.
At discharge the serum creatinine was 3.14 mg/dL and the urinalysis showed hematuria, and protein-creatinine ratio 0.56 (mg/mg Cr). Thirty-nine months after discharge, the creatinine was 1.23 mg/dL, the urinalysis showed persistent nephritis findings and the protein-creatinine ratio 1.28.
Kidney biopsy revealed the membranous glomerulopathy with mild tubulointerstitial nephritis, and all of findings suggested the systemic disease-associated secondary glomerulopathy. To our knowledge our case is the first one of chronic glomerulapathy that is confirmed by kidney biopsy. |
| Key Words:
Acute renal failure, Chronic renal failure, Membranous glomerulopathy, A viral hepatitis |
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